Preferred Label : complementarity determining regions;
MeSH definition : Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE
REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin
chains form a surface that is complementary to the antigen. These regions are also
present in other members of the immunoglobulin superfamily, for example, T-cell receptors
(RECEPTORS, ANTIGEN, T-CELL).;
MeSH synonym : region, complementarity determining; regions, complementarity determining; complementarity-determining region; regions, complementarity-determining; complementarity determining region; hypervariable regions, immunoglobulin; hypervariable region, immunoglobulin; immunoglobulin hypervariable region; immunoglobulin hypervariable regions; region, immunoglobulin hypervariable; regions, immunoglobulin hypervariable; Complementarity-Determining regions;
CISMeF synonym : regions, hypervariable; hypervariable regions; hypervariable region;
MeSH hyponym : complementarity determining region 3; complementarity determining region 2; complementarity determining region 1; Complementarity-Determining Region 3; Complementarity-Determining Region 3s; Third Complementarity-Determining Region; Complementarity-Determining Region, Third; Complementarity-Determining Regions, Third; Third Complementarity Determining Region; Third Complementarity-Determining Regions; Complementarity Determining Region III; Complementarity Determining Region I; Complementarity Determining Region II;
Wikipedia link : https://en.wikipedia.org/wiki/Complementarity determining regions;
Is substance : O;
Origin ID : D022801;
UMLS CUI : C0021024;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE
REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin
chains form a surface that is complementary to the antigen. These regions are also
present in other members of the immunoglobulin superfamily, for example, T-cell receptors
(RECEPTORS, ANTIGEN, T-CELL).
