receptors, antigen, t-cell

Preferred Label : receptors, antigen, t-cell;

MeSH definition : Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (ANTIGENS, CD3). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.; Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.;

MeSH synonym : t-cell receptors; t-cell antigen receptor; t cell antigen receptor; receptors, t-cell antigen; antigen receptors, t cell; antigen receptor, t-cell; receptor, t-cell antigen; receptors, t-cell; t cell receptors; t-cell receptor; receptor, t-cell; t cell receptor; receptors, t cell antigen; t-cell antigen receptors; antigen receptors, t-cell;

MeSH annotation : GEN; prefer specifics; do not confuse their gamma-delta chains with gamma & delta chains which are subunits of CD3 antigens (index under ANTIGENS, CD3); DF: RECEPT ANTIGEN T CELL; general or unspecified; prefer specifics; do not confuse their gamma-delta chains with gamma and delta chains which are subunits of CD3 antigens (index under ANTIGENS, CD3);

Wikipedia link : https://en.wikipedia.org/wiki/T-cell receptor;

Is substance : O;

Details

Origin ID

D011948;

UMLS CUI

C0034790;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Antigen Receptor [NCIt concept]
- Antigen receptor (substance) [SNOMED CT concept]
- Lymphocyte antigen receptor (substance) [SNOMED CT concept]
- Receptor Cell [NCIt concept]
- T cell receptor [COVID-19 Thesaurus concept]
- T cell receptor beta locus [HGNC gene]
- T cell receptor beta variable 20/OR9-2 (non-functional) [HGNC gene]
- T cell receptor beta variable 21/OR9-2 (pseudogene) [HGNC gene]
- T cell receptor beta variable 24/OR9-2 (pseudogene) [HGNC gene]
- T cell receptor beta variable 25/OR9-2 (pseudogene) [HGNC gene]
- T cell receptor beta variable 29/OR9-2 (non-functional) [HGNC gene]
- T cell receptor gamma constant 1 [HGNC gene]
- T cell receptor gamma constant 2 [HGNC gene]
- T cell receptor gamma joining 1 [HGNC gene]
- T cell receptor gamma joining P [HGNC gene]
- T cell receptor gamma joining P2 [HGNC gene]
- T cell receptor gamma locus [HGNC gene]
- T cell receptor gamma variable 10 (non-functional) [HGNC gene]
- T cell receptor gamma variable 11 (non-functional) [HGNC gene]
- T cell receptor gamma variable 2 [HGNC gene]
- T cell receptor gamma variable 3 [HGNC gene]
- T cell receptor gamma variable 4 [HGNC gene]
- T cell receptor gamma variable 5 [HGNC gene]
- T cell receptor gamma variable 5P (pseudogene) [HGNC gene]
- T cell receptor gamma variable 6 (pseudogene) [HGNC gene]
- T cell receptor gamma variable 7 (pseudogene) [HGNC gene]
- T cell receptor gamma variable 8 [HGNC gene]
- T cell receptor gamma variable 9 [HGNC gene]
- T cell receptor gamma variable A (pseudogene) [HGNC gene]
- T cell receptor gamma variable B (pseudogene) [HGNC gene]
- T-Cell Receptor [NCIt concept]
- T-cell antigen receptor (substance) [SNOMED CT concept]
- antigen receptor [COVID-19 Thesaurus concept]
- antigen receptor site [SNOMED Notion]
- lymphocyte antigen receptor site, nos [SNOMED Notion]
Indexing information
- CD3E protein, human [MeSH Supplementary Concept]
- RL1B monoclonal antibody [MeSH Supplementary Concept]
- TESPA1 protein, human [MeSH Supplementary Concept]
- Tespa1 protein, mouse [MeSH Supplementary Concept]
- pTAC12 protein, mouse [MeSH Supplementary Concept]
Record concept(s)
- receptors, antigen, T-Cell [MeSH concept]
Related MeSH Supplementary Concept(s)
- ALT-801 [MeSH Supplementary Concept]
- CD19-specific chimeric antigen receptor [MeSH Supplementary Concept]
- CD3 epsilon, wallaby [MeSH Supplementary Concept]
- CD3epsilon protein, bovine [MeSH Supplementary Concept]
- CD8 receptor [MeSH Supplementary Concept]
- CTL019 chimeric antigen receptor [MeSH Supplementary Concept]
- IL13-zetakine [MeSH Supplementary Concept]
- MLR3 activation antigen [MeSH Supplementary Concept]
- Sts-2 protein, mouse [MeSH Supplementary Concept]
- T cell receptor-V(beta)8-39-59 peptide [MeSH Supplementary Concept]
- TCRzeta protein, bos taurus [MeSH Supplementary Concept]
- Valpha24 protein, human [MeSH Supplementary Concept]
- antigen T cell receptor, epsilon chain [MeSH Supplementary Concept]
- antigen T cell receptor, eta-kappa [MeSH Supplementary Concept]
- antigen T cell receptor, iota chain [MeSH Supplementary Concept]
- antigen T cell receptor, zeta chain [MeSH Supplementary Concept]
- antigenic peptide Ealpha52-68 [MeSH Supplementary Concept]
- tisagenlecleucel [MeSH Supplementary Concept]
See also
- CD3 Complex [MeSH Descriptor]
- complementarity determining regions [MeSH Descriptor]
- gene rearrangement, t-lymphocyte [MeSH Descriptor]
- genes, T-Cell receptor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- T-Cell Receptor [NCIt concept]
- T-cell antigen receptor (substance) [SNOMED CT concept]
- t-cell antigen receptor site [SNOMED Notion]

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