Immunoglobulin Heavy Chain

Preferred Label : Immunoglobulin Heavy Chain;

NCIt synonyms : IGH;

NCIt definition : A protein complex that consists of two heavy chains (gamma, alpha, delta, epsilon or mu). The larger of the two immunoglobulin chain types determines the immunoglobulin class (G, A, D, E or M, respectively). The heavy chain molecules exhibit the same structure and composition, which consists of constant, variable, and hypervariable regions.;

Details

Origin ID

C16717;

UMLS CUI

C0021034;

Automatic exact mappings (from CISMeF team)
- IgM.heavy chain [LOINC component]
- Thigh [LOINC System]
- Thigh [LOINC System]
- immunoglobulin alpha-chains [MeSH Descriptor]
- immunoglobulin heavy locus [ORDO Gene]
- thigh [MeSH Descriptor]
Currated CISMeF NLP mapping
- immunoglobulin heavy chains [MeSH Descriptor]
- immunoglobulin heavy chains [MeSH concept]
False automatic mappings
- Immunoglobulin heavy chain (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Immunoglobulin heavy chain (substance) [SNOMED CT concept]
- immunoglobulin heavy chains [MeSH concept]
- immunoglobulin heavy chains [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoglobulin Heavy Locus [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_has_biochemical_function
- Ligand Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin Constant Region [NCIt concept]
- Immunoglobulin Fc [NCIt concept]
- Immunoglobulin Heavy Chain Diversity Region [NCIt concept]
- Immunoglobulin Hinge Region [NCIt concept]
- Immunoglobulin Hypervariable Region [NCIt concept]
- Immunoglobulin Joining Region [NCIt concept]
- Immunoglobulin Variable Region [NCIt concept]
gene_product_is_physical_part_of
- Protein or Riboprotein Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Humoral Immunity [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
has_gene_product_element
- Immunoglobulin Heavy Chain Component [NCIt concept]
- Immunoglobulin Heavy Constant Delta [NCIt concept]
- Immunoglobulin Heavy Constant Gamma 1 [NCIt concept]
- Immunoglobulin Heavy Constant Gamma 2 [NCIt concept]
- Immunoglobulin Heavy Constant Gamma 3 [NCIt concept]
- Immunoglobulin Heavy Constant Gamma 4 [NCIt concept]
- Immunoglobulin Heavy Constant Mu [NCIt concept]
- Immunoglobulin Heavy Diversity 5-18 [NCIt concept]
- Immunoglobulin Heavy Diversity 6-13 [NCIt concept]
- Immunoglobulin Heavy Diversity 6-19 [NCIt concept]
- Immunoglobulin Heavy Joining 4 [NCIt concept]
- Immunoglobulin Heavy Joining 5 [NCIt concept]
- Immunoglobulin Heavy Joining 6 [NCIt concept]
- Immunoglobulin Heavy Variable 3-21 [NCIt concept]
- Immunoglobulin Heavy Variable 4-34 [NCIt concept]
- Immunoglobulin Heavy Variable 4-39 [NCIt concept]

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