CTLA-4 Ligand - CISMeF

Preferred Label : CTLA-4 Ligand;

NCIt synonyms : Cytotoxic T-Lymphocyte-Associated Protein 4 Ligand; CTLA4 Ligand;

NCIt definition : Proteins that bind to cytotoxic T-lymphocyte protein 4, which is expressed on T-cells, and stimulate signaling that may play a role in the inhibition of T-cell activation. This group of proteins includes the T-lymphocyte activation antigens CD80 and CD86, which are expressed on antigen-presenting cells.;

Details

Origin ID

C121501;

UMLS CUI

C4055289;

Biochemical function of gene products
- T-Lymphocyte Activation Antigen CD80 [NCIt concept]
- T-Lymphocyte Activation Antigen CD86 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoglobulin Family Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_has_biochemical_function
- Immunoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin Domain [NCIt concept]
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- Negative Regulation of Lymphocyte Activation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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