ICOS Ligand - CISMeF

Preferred Label : ICOS Ligand;

NCIt synonyms : B7-Like Protein Gl50; CD275; Transmembrane Protein B7-H2 ICOS Ligand; B7 Homologue 2; B7RP-1; CD275 Antigen; Transmembrane Protein B7-H2; B7-H2; B7-Related Protein 1;

NCIt definition : ICOS ligand (302 aa, 33 kDa) is encoded by the human ICOSLG gene. This protein is involved in lymphocyte proliferation, costimulation of T-cells and the modulation of B-cell proliferation and differentiation.;

Details

Origin ID

C118943;

UMLS CUI

C0961804;

Automatic exact mappings (from CISMeF team)
- Inducible t-cell costimulator ligand [OMIM gene]
- inducible T cell costimulator ligand [HGNC gene]
Currated CISMeF NLP mapping
- inducible T-Cell Co-Stimulator ligand [MeSH Descriptor]
OMIM relation
- Inducible t-cell costimulator ligand [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- ICOSLG protein, human [MeSH Supplementary Concept]
- ICOSLG protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ICOSLG Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Dendritic Cell [NCIt concept]
- Monocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- B Cell Proliferation [NCIt concept]
- B-Cell Differentiation [NCIt concept]
- Immune System Process [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- T-Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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