Shelterin - CISMeF

Preferred Label : Shelterin;

NCIt synonyms : Telosome; Shelterin Complex;

NCIt definition : A protein complex that is physically bound to chromosomal telomeres and plays a role in both the elongation and maintenance of telomeric repeats.;

NCIt note : The mammalian shelterin complex is comprised of six proteins: telomeric repeat-binding factor (TERF) 1, TERF 2, TERF1-interacting nuclear factor 2, protection of telomeres protein 1, telomeric repeat-binding factor 2-interacting protein 1, and adrenocortical dysplasia protein homolog.;

Details

Origin ID

C118795;

UMLS CUI

C3889653;

Currated CISMeF NLP mapping
- Shelterin Complex [MeSH concept]
- Shelterin Complex [MeSH Descriptor]
- shelterin complex [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Shelterin Complex [MeSH Descriptor]
gene_product_has_associated_anatomy
- Telomere [NCIt concept]
gene_product_plays_role_in_biological_process
- Telomere Capping [NCIt concept]
- Telomere Maintenance [NCIt concept]
has_gene_product_element
- Adrenocortical Dysplasia Protein Homolog [NCIt concept]
- Protection of Telomeres Protein 1 [NCIt concept]
- TERF1-Interacting Nuclear Factor 2 [NCIt concept]
- Telomeric Repeat-Binding Factor 1 [NCIt concept]
- Telomeric Repeat-Binding Factor 2 [NCIt concept]
- Telomeric Repeat-Binding Factor 2-Interacting Protein 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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