FYVE, RhoGEF and PH Domain-Containing Protein 5

Preferred Label : FYVE, RhoGEF and PH Domain-Containing Protein 5;

NCIt synonyms : Zinc Finger FYVE Domain-Containing Protein 23; FGD5;

NCIt definition : FYVE, RhoGEF and PH domain-containing protein 5 (1462 aa, 160 kDa) is encoded by the human FGD5 gene. This protein plays a role in both signal transduction and the reorganization of the actin cytoskeleton.;

Details

Origin ID

C105933;

UMLS CUI

C3492134;

Automatic exact mappings (from CISMeF team)
- Fyve, rhogef, and ph domain-containing protein 5 [OMIM gene]
OMIM relation
- Fyve, rhogef, and ph domain-containing protein 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FGD5 protein, human [MeSH Supplementary Concept]
- FGD5 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FGD5 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- F-actin [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Regulation of Cell Shape [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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