MeSH note : bioinformatics analysis shows FTO shares sequence motifs with Fe(II)- & 2-oxoglutarate-dependent
oxygenases; recombinant Fto catalyzes the Fe(II)- & 2OG-dependent demethylation of
3-methylthymine in single-stranded DNA; Fto mRNA is most abundant in brain;
MeSH synonym : fat mass and obesity associated protein, mouse; FTO (fat mass and obesity associated) protein, mouse;