Preferred Label : neratinib;

MeSH note : an orally active, irreversible inhibitor of the HER-2 tyrosine kinase;

CISMeF synonym : HKI 272;

MeSH synonym : N-(4-(3-chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide;

MeSH hyponym : HKI272; HKI-272;

Is substance : O;

UNII : JJH94R3PWB;

Details


Main resources

You can consult :


https://www.has-sante.fr/jcms/p_3443498/fr/nerlynx-neratinib-cancer-du-sein
2023
false
false
false
France
treatment outcome
insurance, health, reimbursement
Adjuvant Therapy
Early-Stage HER2 Positive Breast Cancer
adult
administration, oral
Product containing precisely neratinib (as neratinib maleate) 40 milligram/1 each conventional release oral tablet (clinical drug)
neratinib
HER2 Inhibitor
evaluation of the transparency committee
breast neoplasms
Nerlynx
neratinib

---
https://www.has-sante.fr/jcms/p_3191460/fr/nerlynx
2020
false
false
false
France
neratinib
administration, oral
insurance, health, reimbursement
adult
breast neoplasms
Adjuvant Chemotherapy
Hormone Receptor-Positive Breast Carcinoma
receptor, erbB-2
Trastuzumab
treatment outcome
Product containing precisely neratinib (as neratinib maleate) 40 milligram/1 each conventional release oral tablet (clinical drug)
evaluation of the transparency committee
neratinib
quinolines

---
https://www.ema.europa.eu/medicines/human/EPAR/Nerlynx
2018
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
product surveillance, postmarketing
neratinib
breast neoplasms
recurrence
HER2 positive breast cancer
Hormone receptor positive malignant neoplasm of breast (disorder)
administration, oral
breast neoplasms
protein-tyrosine kinases
receptor, erbB-2
adult
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
Product containing precisely neratinib (as neratinib maleate) 40 milligram/1 each conventional release oral tablet (clinical drug)
Tyrosine Kinase Inhibitors
neratinib
neratinib
quinolines
quinolines

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Nous contacter.
20/05/2024


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