Preferred Label : ambrisentan;

MeSH note : RN given for the (( -)-2S)-isomer; an ET(A) receptor antagonist; studied for use as in pulmonary arterial hypertension;

CISMeF synonym : BSF 208075; LU 208075; gilead brand of ambrisentan; letairis;

MeSH synonym : ( )-(2S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid; ( )-ambrisentan; (S)-ambrisentan;

MeSH Hyperonym : ( -)-ambrisentan;

MeSH hyponym : LU-208075; LU208075; BSF-208075; BSF208075; GSK 1325760A; GSK1325760A; GSK 1325760; GSK-1325760A; GSK1325760; (R)-ambrisentan; ambrisentan, (R)-; (-)-ambrisentan;

MeSH CAS label : 2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenyl-propanoic acid;

MeSH Related Number : 177036-94-1; 7B43003091; Q1BX7HE63A;

Registry Number MeSH : 177036-94-1;

Is substance : O;

UNII : HW6NV07QEC;

Details


Main resources

You can consult :


https://www.has-sante.fr/jcms/p_3185845/fr/ambrisentan-teva
2020
false
false
false
France
drugs, generic
ambrisentan
evaluation of the transparency committee
ambrisentan
phenylpropionates
pyridazines

---
https://www.has-sante.fr/jcms/p_3184674/fr/ambrisentan-mylan
2020
false
false
false
France
drugs, generic
ambrisentan
evaluation of the transparency committee
ambrisentan
phenylpropionates
pyridazines
phenylpropionates
pyridazines

---
https://www.has-sante.fr/jcms/p_3169251/fr/ambrisentan-reddy-pharma
2020
false
false
false
France
drugs, generic
ambrisentan
evaluation of the transparency committee
ambrisentan
phenylpropionates
pyridazines

---
https://www.has-sante.fr/jcms/p_3191481/fr/ambrisentan-ohre-pharma
2020
false
false
false
France
drugs, generic
ambrisentan
evaluation of the transparency committee
ambrisentan
phenylpropionates
pyridazines
phenylpropionates
pyridazines

---
https://www.has-sante.fr/jcms/p_3159933/fr/ambrisentan-eg
2020
false
false
false
France
ambrisentan
drugs, generic
evaluation of the transparency committee
ambrisentan

---
https://www.ema.europa.eu/en/medicines/human/EPAR/ambrisentan-mylan
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
drugs, generic
ambrisentan
ambrisentan
antihypertensive agents
antihypertensive agents
ambrisentan
hypertension, pulmonary
adult
drug therapy, combination
administration, oral
Endothelin A Receptor Antagonists
Endothelin A Receptor Antagonists
aged
drug interactions
pregnancy
breast feeding
fertility
drug evaluation, preclinical
phenylpropionates
pyridazines
phenylpropionates
pyridazines

---
https://www.has-sante.fr/jcms/p_3135595/fr/ambrisentan-accord
2019
false
false
false
France
French
drugs, generic
evaluation of the transparency committee
ambrisentan
ambrisentan
Perianal abscess
generations
dandruff
devices
tablets
family characteristics
Brain abscess
device, nos
Set, Psychology
seborrhea sicca
dandruff
equipment and supplies
phenylpropionates
pyridazines
phenylpropionates
pyridazines

---
http://www.has-sante.fr/portail/jcms/c_2751870/fr/volibris
https://www.has-sante.fr/portail/jcms/c_2751870/fr/volibris-ambrisentan-antihypertenseur
2017
false
false
false
France
French
evaluation of the transparency committee
guidelines for drug use
drug therapy, combination
treatment outcome
hypertension, pulmonary
ambrisentan
ambrisentan
adult
Tadalafil
administration, oral
orphan drug production
ambrisentan
phenylpropionates
pyridazines
phenylpropionates
pyridazines
phenylpropionates
pyridazines

---
https://www.ema.europa.eu/medicines/human/EPAR/Volibris
2012
false
United Kingdom
English
French
Endothelin A Receptor Antagonists
Endothelin A Receptor Antagonists
syndication feed
ambrisentan
ambrisentan
phenylpropionates
pyridazines
pyridazines
drug approval
drug labeling
treatment outcome
drug evaluation
orphan drug production
tablets
administration, oral
hypertension, pulmonary
adult
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
phenylpropionates
ambrisentan
drug evaluation
summary of product characteristics
package leaflet

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68499606
2012
France
summary of product characteristics
package leaflet
tablets
ambrisentan
ambrisentan

---
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2012/14802a-fra.php
https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2012/14803a-fra.php
2012
false
Canada
French
English
pharmacovigilance note
Endothelin A Receptor Antagonists
phenylpropionates
pyridazines
ambrisentan
idiopathic pulmonary fibrosis
ambrisentan
disease progression
hypertension, pulmonary
Contraindications, Drug

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66848183
2012
France
summary of product characteristics
package leaflet
ambrisentan
ambrisentan
tablets

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-05/synthese_davis_reevaluation_htap_2011-05-12_12-18-35_386.pdf
http://www.has-sante.fr/portail/jcms/c_1053751/medicaments-de-lhypertension-arterielle-pulmonaire-idiopathique-ou-associee-a-une-connectivite
2011
false
France
French
evaluation of the transparency committee
guidelines for drug use
Sildenafil Citrate
Tadalafil
hypertension, pulmonary
collagen diseases
epoprostenol
antihypertensive agents
sulfonamides
treprostinil
epoprostenol
phosphodiesterase 5 inhibitors
iloprost
receptors, endothelin
ambrisentan
phenylpropionates
DERMATITIS
survival analysis
Antihypertensives for pulmonary arterial hypertension
treatment outcome
pyridazines
Bosentan

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00307
2011
false
false
false
Canada
drug information
ambrisentan
tablets
ambrisentan

---
http://www.has-sante.fr/portail/jcms/c_684166/volibris
http://www.has-sante.fr/portail/upload/docs/application/pdf/2008-08/ct-5603_volibris_.pdf
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-12/volibris_ct_5603.pdf
2008
France
French
ambrisentan
hypertension, pulmonary
orphan drug production
administration, oral
phenylpropionates
pyridazines
ambrisentan
adult
aged
treatment outcome
receptors, endothelin
phenylpropionates
pyridazines
evaluation of the transparency committee

---
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25/04/2025


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