Bosentan - CISMeF

Preferred Label : Bosentan;

MeSH definition : A sulfonamide and pyrimidine derivative that acts as a dual endothelin receptor antagonist used to manage PULMONARY HYPERTENSION and SYSTEMIC SCLEROSIS.;

MeSH synonym : 4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide;

MeSH hyponym : Ro 47 0203; Ro 470203; Ro-47-0203;

MeSH CAS label : Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)-;

MeSH Related Number : 147536-97-8 (Bosentan); XUL93R30K2;

UNII : Q326023R30;

Details

Origin ID

D000077300;

UMLS CUI

C0252643;

ATC code(s)
- bosentan [ATC Code]
ATC code(s)
- bosentan [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
MeSH indexing information
- receptors, endothelin [MeSH Descriptor]
Pharmacological action(s)
- Endothelin Receptor Antagonists [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
Record concept(s)
- Bosentan [MeSH concept]
- bosentan anhydrous [MeSH concept]
- bosentan monohydrate [MeSH concept]
- ro 47-0203 [MeSH concept]
- tracleer [MeSH concept]
See also inter- (CISMeF)
- Bosentan Anhydrous [NCIt concept]
- Product containing bosentan (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- bosentan [ATC Code]

Keyword's position in hierarchy(ies) :

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