Preferred Label : Endothelin-1;
MeSH definition : A 21-amino acid peptide produced in a variety of tissues including endothelial and
vascular smooth-muscle cells, neurons and astrocytes in the central nervous system,
and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation,
and hormone production. (N Eng J Med 1995;333(6):356-63);
MeSH synonym : endothelin type 1; endothelin 1;
CISMeF synonym : et-1 (endothelin-1);
MeSH hyponym : Preproendothelin-1; proendothelin (1-38); Big Endothelin; Big Endothelin-1; Big Endothelin 1; Endothelin-1, Big; Endothelin, Big; Preproendothelin 1; Preproendothelin; Proendothelin-1 Precursor; Precursor, Proendothelin-1; Proendothelin 1 Precursor;
MeSH Related Number : Preproendothelin-1; proendothelin (1-38); 114540-95-3; 122462-75-3;
Related CAS MeSH : 122462-75-3 (Proendothelin (1-38)); 114540-95-3 (Preproendothelin-1);
MeSH annotation : /drug eff permitted;
Wikipedia link : https://en.wikipedia.org/wiki/Endothelin-1;
Is substance : O;
Origin ID : D019332;
UMLS CUI : C0079281;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- See also (suggested by CISMeF)
- Semantic type(s)
A 21-amino acid peptide produced in a variety of tissues including endothelial and
vascular smooth-muscle cells, neurons and astrocytes in the central nervous system,
and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation,
and hormone production. (N Eng J Med 1995;333(6):356-63)
