Preferred Label : abacavir;
MeSH note : a carbocyclic nucleoside with potent selective anti-HIV activity; structure given
in first source;
CISMeF synonym : 1592U89; GSK brand of abacavir sulfate; ziagen;
MeSH synonym : (-)-cis-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol; avacavir; (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol;
MeSH hyponym : (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol succinate
(1:1) (salt); abacavir sulphate; trans-abacavir R,R-; DRG0257; DRG 0257; abacavir, trans-; abacavir, trans-, ( -)-; ((1R,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-cyclopent-2-enyl)methanol; 2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-,
rel-, sulfate (2:1); abacavir sulfate, ( -)-; abacavir sulfate racemic; abacavir, (1R,4S)-; abacavir enantiomer; abacavir, ( )-; ((1R,4S)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol; 2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1R,4S)-,
sulfate (2:1); (1R,4S)-abacavir sulfate; ( )-abacavir sulfate; abacavir sulfate, (1R,4S)-; 2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, hydrochloride,
hydrate (1:1:1), (1S,4R)-;
MeSH Related Number : abacavir succinate; abacavir sulfate; 40FH6D8CHK; J220T4J9Q2; 0903H757IU; 1PPL256S5A; 6BVN3YCO99; GZP7A66C3C; PMA9EH08PM; X9A7099R51;
Related CAS MeSH : 40FH6D8CHK (abacavir succinate); J220T4J9Q2 (abacavir sulfate);
CISMeF hyponym : sulfate d'abacavir;
Is substance : O;
UNII : WR2TIP26VS;
InChIKey : MCGSCOLBFJQGHM-SCZZXKLOSA-N;
Origin ID : C106538;
UMLS CUI : C0663655;
ATC code(s)
- MeSH term(s) associated for indexing
- Pharmacological action(s)
- Record concept(s)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
http://www.has-sante.fr/portail/jcms/c_779534/detection-de-l-allele-hla-b5701-prealable-au-traitement-par-abacavir
2016
false
false
false
France
French
drug hypersensitivity
genetic testing
abacavir
drug hypersensitivity
HLA-B*57:01 antigen
HLA-B*5701 assay
health technology assessment
reverse transcriptase inhibitors
hypersensitivity, delayed
mass screening
dideoxynucleosides
HLA-B antigens
---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=64287253
2015
false
false
false
France
French
summary of product characteristics
evaluation of the transparency committee
package leaflet
lamivudine, abacavir and dolutegravir
lamivudine
abacavir sulfate
dolutegravir sodium
drug combinations
abacavir
dolutegravir
dideoxynucleosides
heterocyclic compounds, 3-ring
---
https://www.ema.europa.eu/medicines/human/EPAR/Triumeq
2014
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
drug combinations
abacavir sulfate
abacavir sulfate
dolutegravir sodium
dolutegravir sodium
lamivudine
lamivudine
anti-hiv agents
anti-hiv agents
hiv infections
adolescent
adult
aged
administration, oral
tablets
lamivudine, abacavir and dolutegravir
HLA-B*57:01 antigen
genetic testing
drug hypersensitivity
reverse transcriptase inhibitors
reverse transcriptase inhibitors
HIV integrase inhibitors
HIV integrase inhibitors
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
abacavir
abacavir
HLA-B antigens
dideoxynucleosides
dideoxynucleosides
---
http://www.has-sante.fr/portail/jcms/c_2008464/fr/triumeq
http://www.has-sante.fr/portail/jcms/c_2008464/fr/triumeq-dolutegravir/abacavir/lamivudine-association-fixe-d-antiretroviraux
2014
false
false
false
France
French
evaluation of the transparency committee
guidelines for drug use
administration, oral
insurance, health, reimbursement
treatment outcome
drug combinations
dolutegravir
dolutegravir
abacavir
abacavir
lamivudine
lamivudine
lamivudine, abacavir and dolutegravir
reverse transcriptase inhibitors
reverse transcriptase inhibitors
anti-hiv agents
anti-hiv agents
HIV integrase inhibitors
HIV integrase inhibitors
adult
adolescent
hiv infections
HIV-1
HLA-B*57:01 antigen
human immunodeficiency virus i infection
Contraindications, Procedure
heterocyclic compounds, 3-ring
heterocyclic compounds, 3-ring
dideoxynucleosides
dideoxynucleosides
HLA-B antigens
Contraindications, Drug
---
http://www.cochrane.org/fr/CD008270
2013
United Kingdom
France
French
review of literature
hiv infections
treatment outcome
antiretroviral therapy, highly active
anti-hiv agents
abacavir
dideoxynucleosides
french abstract
---
http://www.cochrane.org/fr/CD005481/association-abacavir-lamivudine-zidovudine-pour-le-traitement-de-linfection-par-le-vih-et-du-sida
2013
false
false
United Kingdom
France
French
meta-analysis
french abstract
hiv infections
antiviral agents
acquired immunodeficiency syndrome
lamivudine
zidovudine
drug combinations
abacavir, lamivudine, and zidovudine drug combination
abacavir
treatment outcome
dideoxynucleosides
---
https://www.ema.europa.eu/medicines/human/EPAR/Kivexa
2012
United Kingdom
English
French
syndication feed
lamivudine
acquired immunodeficiency syndrome
dideoxynucleosides
reverse transcriptase inhibitors
drug combinations
hiv infections
adult
adolescent
HIV-1
anti-hiv agents
lamivudine and abacavir
dideoxynucleosides
reverse transcriptase inhibitors
anti-hiv agents
lamivudine
abacavir
abacavir, lamivudine drug combination
abacavir
abacavir, lamivudine drug combination
abacavir sulfate
abacavir sulfate
drug evaluation
summary of product characteristics
package leaflet
---
https://www.ema.europa.eu/medicines/human/EPAR/Ziagen
2011
United Kingdom
French
English
syndication feed
drug evaluation
reverse transcriptase inhibitors
treatment outcome
anti-hiv agents
hiv infections
acquired immunodeficiency syndrome
dideoxynucleosides
abacavir
anti-hiv agents
dideoxynucleosides
reverse transcriptase inhibitors
abacavir
abacavir sulfate
abacavir sulfate
abacavir
package leaflet
drug evaluation
summary of product characteristics
---
https://www.ema.europa.eu/medicines/human/EPAR/Trizivir
2011
United Kingdom
French
English
syndication feed
dideoxynucleosides
anti-hiv agents
lamivudine
zidovudine
reverse transcriptase inhibitors
acquired immunodeficiency syndrome
adult
hiv infections
treatment outcome
drug evaluation
drug combinations
zidovudine, lamivudine and abacavir
dideoxynucleosides
anti-hiv agents
lamivudine
zidovudine
reverse transcriptase inhibitors
abacavir
abacavir, lamivudine, and zidovudine drug combination
abacavir sulfate
abacavir sulfate
abacavir
abacavir, lamivudine, and zidovudine drug combination
dideoxynucleosides
drug evaluation
package leaflet
summary of product characteristics
---
http://www.has-sante.fr/portail/jcms/c_1065589/ziagen
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-07/ziagen_-_ct_6935.pdf
2011
France
French
evaluation of the transparency committee
abacavir sulfate
abacavir
administration, oral
insurance, health, reimbursement
reverse transcriptase inhibitors
anti-hiv agents
dideoxynucleosides
abacavir
hiv infections
drug therapy, combination
adult
adolescent
child
drug utilization
treatment outcome
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-05/kivexa_-_ct-7521.pdf
http://www.has-sante.fr/portail/jcms/c_1054868/kivexa
2011
France
French
evaluation of the transparency committee
dideoxynucleosides
administration, oral
drug combinations
lamivudine
abacavir
abacavir, lamivudine drug combination
insurance, health, reimbursement
lamivudine and abacavir
anti-hiv agents
adult
adolescent
risk assessment
treatment outcome
abacavir sulfate
dideoxynucleosides
---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-05/trizivir_-_ct-7080.pdf
http://www.has-sante.fr/portail/jcms/c_1051920/trizivir
2011
France
French
evaluation of the transparency committee
abacavir, lamivudine, and zidovudine drug combination
drug combinations
lamivudine
zidovudine
abacavir
dideoxynucleosides
anti-hiv agents
administration, oral
insurance, health, reimbursement
zidovudine, lamivudine and abacavir
adult
abacavir, lamivudine, and zidovudine drug combination
treatment outcome
abacavir sulfate
dideoxynucleosides
---
http://www.meddispar.fr/index.php/medicaments/3610928
2010
France
French
drug combinations
administration, oral
legislation, drug
drug prescriptions
abacavir, lamivudine, and zidovudine drug combination
lamivudine
abacavir
zidovudine, lamivudine and abacavir
zidovudine
dideoxynucleosides
abacavir sulfate
drug information
---
http://www.has-sante.fr/portail/jcms/c_718918/trizivir
2008
France
French
reverse transcriptase inhibitors
lamivudine
dideoxynucleosides
drug combinations
zidovudine
administration, oral
tablets
insurance, health, reimbursement
anti-hiv agents
adult
hiv infections
genetic testing
HLA-B antigens
drug hypersensitivity
abacavir
abacavir, lamivudine, and zidovudine drug combination
HLA-B*57:01 antigen
zidovudine, lamivudine and abacavir
abacavir sulfate
dideoxynucleosides
HLA-B antigens
evaluation of the transparency committee
---
http://www.meddispar.fr/medicaments/3657284
2008
France
French
lamivudine
dideoxynucleosides
drug combinations
tablets
administration, oral
drug prescriptions
legislation, drug
abacavir
abacavir, lamivudine drug combination
lamivudine and abacavir
abacavir sulfate
drug information
---
http://www.meddispar.fr/medicaments/3610897
2008
France
French
dideoxynucleosides
tablets
administration, oral
legislation, drug
drug prescriptions
abacavir
abacavir
abacavir sulfate
drug information
---
http://www.has-sante.fr/portail/jcms/c_718939/ziagen
2008
France
French
pharmaceutical solutions
reverse transcriptase inhibitors
dideoxynucleosides
anti-hiv agents
administration, oral
genetic testing
tablets
hiv infections
drug hypersensitivity
anti-hiv agents
reverse transcriptase inhibitors
HLA-B antigens
abacavir
abacavir
HLA-B*57:01 antigen
abacavir
dideoxynucleosides
abacavir sulfate
abacavir sulfate
dideoxynucleosides
HLA-B antigens
evaluation of the transparency committee
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68556562
2008
France
French
dideoxynucleosides
administration, oral
tablets
abacavir
abacavir
abacavir sulfate
drug information
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62070450
2008
France
French
pharmaceutical solutions
administration, oral
dideoxynucleosides
abacavir
abacavir
abacavir sulfate
drug information
---
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2008/14488a-fra.php
2008
Canada
French
English
Cardiotoxicity
reverse transcriptase inhibitors
dideoxynucleosides
drug combinations
lamivudine
myocardial infarction
anti-hiv agents
canada
zidovudine
risk assessment
abacavir
abacavir, lamivudine, and zidovudine drug combination
abacavir, lamivudine drug combination
abacavir sulfate
dideoxynucleosides
pharmacovigilance note
---
http://www.has-sante.fr/portail/jcms/c_719595/kivexa
2008
France
French
abacavir
abacavir, lamivudine drug combination
HLA-B*57:01 antigen
reverse transcriptase inhibitors
lamivudine
dideoxynucleosides
drug combinations
administration, oral
tablets
genetic testing
anti-hiv agents
HLA-B antigens
hiv infections
drug therapy, combination
adult
adolescent
drug hypersensitivity
lamivudine and abacavir
abacavir sulfate
dideoxynucleosides
HLA-B antigens
evaluation of the transparency committee
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69855489
2008
France
French
abacavir
abacavir, lamivudine drug combination
drug combinations
tablets
dideoxynucleosides
lamivudine
administration, oral
lamivudine and abacavir
abacavir sulfate
drug information
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64976070
2008
France
French
drug combinations
zidovudine
dideoxynucleosides
lamivudine
administration, oral
abacavir
abacavir, lamivudine, and zidovudine drug combination
zidovudine, lamivudine and abacavir
abacavir sulfate
drug information
---
http://www.meddispar.fr/medicaments/3610928
2008
France
French
lamivudine
zidovudine
drug combinations
drug prescriptions
legislation, drug
abacavir, lamivudine, and zidovudine drug combination
abacavir
zidovudine, lamivudine and abacavir
abacavir sulfate
dideoxynucleosides
drug information
---
http://www.meddispar.fr/medicaments/3610905
2008
France
French
legislation, drug
drug prescriptions
dideoxynucleosides
pharmaceutical solutions
administration, oral
abacavir
abacavir
abacavir sulfate
drug information
---
http://www.has-sante.fr/portail/display.jsp?id=c_400208
2005
France
French
anti-hiv agents
reverse transcriptase inhibitors
drug combinations
tablets
dideoxynucleosides
lamivudine
insurance, health, reimbursement
hiv infections
administration, oral
adult
adolescent
drug therapy, combination
treatment outcome
drug resistance, viral
drug hypersensitivity
lamivudine
anti-hiv agents
dideoxynucleosides
reverse transcriptase inhibitors
abacavir, lamivudine drug combination
abacavir
abacavir
abacavir, lamivudine drug combination
lamivudine and abacavir
abacavir sulfate
abacavir sulfate
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/display.jsp?id=c_400035
2004
France
French
tablets
reverse transcriptase inhibitors
anti-hiv agents
dideoxynucleosides
pharmaceutical solutions
administration, oral
hiv infections
adult
child
infant
treatment outcome
reverse transcriptase inhibitors
anti-hiv agents
dideoxynucleosides
drug hypersensitivity
drug resistance, viral
insurance, health, reimbursement
abacavir
abacavir
abacavir
abacavir sulfate
abacavir sulfate
dideoxynucleosides
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/display.jsp?id=c_399930
2003
France
French
reverse transcriptase inhibitors
drug combinations
tablets
zidovudine
dideoxynucleosides
lamivudine
administration, oral
insurance, health, reimbursement
anti-hiv agents
hiv infections
adult
aged
treatment outcome
dideoxynucleosides
drug hypersensitivity
anti-hiv agents
reverse transcriptase inhibitors
abacavir
abacavir, lamivudine, and zidovudine drug combination
abacavir, lamivudine, and zidovudine drug combination
abacavir
zidovudine, lamivudine and abacavir
abacavir sulfate
abacavir sulfate
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/display.jsp?id=c_399405
2002
France
French
tablets
reverse transcriptase inhibitors
anti-hiv agents
dideoxynucleosides
child
infant
adolescent
pharmaceutical solutions
administration, oral
hiv infections
treatment outcome
reverse transcriptase inhibitors
anti-hiv agents
dideoxynucleosides
drug hypersensitivity
abacavir
abacavir
abacavir
abacavir sulfate
abacavir sulfate
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/display.jsp?id=c_399056
2001
France
French
reverse transcriptase inhibitors
drug combinations
tablets
zidovudine
dideoxynucleosides
lamivudine
administration, oral
hiv infections
anti-hiv agents
adult
treatment outcome
abacavir
abacavir, lamivudine, and zidovudine drug combination
zidovudine, lamivudine and abacavir
abacavir sulfate
dideoxynucleosides
evaluation of the transparency committee
---
