Preferred Label : HLA-B antigens;
MeSH definition : Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable
alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities.
Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition
to rheumatoid and other autoimmune disorders. Like other class I HLA determinants,
they are involved in the cellular immune reactivity of cytolytic T lymphocytes.;
MeSH synonym : antigens, hla b; hla-b; antigens, hla-b; HLA B antigens; HLA-B Antigen; Antigen, HLA-B; HLA B Antigen;
MeSH annotation : general; prefer specifics;
Is substance : O;
Origin ID : D015235;
UMLS CUI : C0019737;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Record concept(s)
Related MeSH Supplementary Concept(s)
- HLA-B58 [MeSH Supplementary Concept]
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable
alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities.
Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition
to rheumatoid and other autoimmune disorders. Like other class I HLA determinants,
they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
http://www.has-sante.fr/portail/jcms/c_779534/detection-de-l-allele-hla-b5701-prealable-au-traitement-par-abacavir
2016
false
false
false
France
French
drug hypersensitivity
genetic testing
abacavir
drug hypersensitivity
HLA-B*57:01 antigen
HLA-B*5701 assay
health technology assessment
reverse transcriptase inhibitors
hypersensitivity, delayed
mass screening
dideoxynucleosides
HLA-B antigens
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