Preferred Label : HLA-B antigens;

MeSH definition : Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.;

MeSH synonym : antigens, hla b; hla-b; antigens, hla-b; HLA B antigens; HLA-B Antigen; Antigen, HLA-B; HLA B Antigen;

MeSH annotation : general; prefer specifics;

Is substance : O;

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Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.

http://www.has-sante.fr/portail/jcms/c_779534/detection-de-l-allele-hla-b5701-prealable-au-traitement-par-abacavir
2016
false
false
false
France
French
drug hypersensitivity
genetic testing
abacavir
drug hypersensitivity
HLA-B*57:01 antigen
HLA-B*5701 assay
health technology assessment
reverse transcriptase inhibitors
hypersensitivity, delayed
mass screening
dideoxynucleosides
HLA-B antigens

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26/04/2025


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