TNK-tissue plasminogen activator

Preferred Label : TNK-tissue plasminogen activator;

MeSH note : a genetically-engineered variant of tissue plasminogen activator with amino acid substitutions at Thr(103) by Asn, Asn(117) by glutamine, and 4 amino acids (Lys, His, Arg, Arg) replaced by 4 alanines at the 3rd site;

MeSH synonym : TNK-TPA;

Registry Number MeSH : EC 3.4.21.-; EC 3.4.21.68;

Is substance : O;

UNII : EC 3.4.21.68;

Details

Origin ID

C104096;

UMLS CUI

C0535245;

Automatic exact mappings (from CISMeF team)
- Kallikrein-11 [NCIt concept]
- Kallikrein-15 [NCIt concept]
- Lactotransferrin [NCIt concept]
- Tenecteplase [NCIt concept]
MeSH term(s) associated for indexing
- tissue plasminogen activator [MeSH Descriptor]
Record concept(s)
- TNK-tissue plasminogen activator [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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