Preferred Label : methylnaltrexone;

MeSH note : RN given refers to parent cpd(5alpha)-isomer;

CISMeF synonym : MRZ 2663BR; MRZ-2663; naltrexone methylbromide; naltrexonium methiodide; relistor;

MeSH synonym : 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinanium-6-one; quaternary ammonium naltrexone; morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, (5alpha)-; morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, (5alpha)-; (5alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-17-ium-6-one;

MeSH hyponym : N-methylnaltrexone bromide; morphinan-17-ium-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-, bromide, (5alpha,17R)-; naltrexone MB; naltrexone methobromide; methylnaltrexone bromide; methyl-naltrexone hydrobromide;

MeSH Related Number : 73232-52-7 (bromide(5alpha)-isomer); 83387-25-1 (methylnaltrexone); RFO6IL3D3M;

Registry Number MeSH : 83387-25-1;

related registry number list (CISMeF) : 73232-52-7 (bromide(5alpha)-isomer);

Is substance : O;

UNII : 0RK7M7IABE;

Details


Main resources

You can consult :


https://www.has-sante.fr/portail/jcms/c_2908447/fr/relistor
2019
true
false
France
French
Drug-induced constipation (disorder)
narcotic antagonists
naltrexone
quaternary ammonium compounds
constipation
constipation
analgesics, opioid
insurance, health, reimbursement
terminal care
pharmaceutical solutions
receptors, opioid, mu
adult
treatment outcome
injections, subcutaneous
methylnaltrexone
methylnaltrexone bromide
evaluation of the transparency committee

---
https://www.has-sante.fr//portail/jcms/c_2749479/fr/relistor
2017
false
France
French
guidelines for drug use
Opioid-Induced Constipation
narcotic antagonists
naltrexone
quaternary ammonium compounds
analgesics, opioid
insurance, health, reimbursement
terminal care
pharmaceutical solutions
receptors, opioid, mu
adult
treatment outcome
injections, subcutaneous
methylnaltrexone
methylnaltrexone bromide
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/jcms/c_2749479/fr/relistor
2017
false
false
false
France
French
evaluation of the transparency committee
naltrexone methylbromide
methylnaltrexone bromide
Opioid-Induced Constipation
methylnaltrexone
quaternary ammonium compounds
naltrexone
naltrexone

---
https://www.minerva-ebp.be/fr/article/191
2012
false
false
minerva-ebm.be
Belgium
Dutch
French
critical appraisal or critical reading
quaternary ammonium compounds
naltrexone
Opioid-Induced Constipation
injections, subcutaneous
adult
chronic disease
analgesics, opioid
methylnaltrexone
pain
treatment outcome
methylnaltrexone bromide

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60594326
2012
France
summary of product characteristics
package leaflet
bromides
naltrexone methylbromide
injections
methylnaltrexone

---
https://www.ema.europa.eu/medicines/human/EPAR/Relistor
2011
false
United Kingdom
French
English
Drug-induced constipation (disorder)
syndication feed
naltrexone
narcotic antagonists
constipation
quaternary ammonium compounds
adult
constipation
analgesics, opioid
narcotic antagonists
naltrexone
naltrexone
quaternary ammonium compounds
drug approval
drug labeling
pregnancy
breast feeding
treatment outcome
injections, subcutaneous
drug interactions
drug evaluation, preclinical
methylnaltrexone
methylnaltrexone
methylnaltrexone bromide
drug evaluation
summary of product characteristics
package leaflet

---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00124
2011
false
false
false
Canada
drug information
methylnaltrexone
naltrexone methylbromide
bromides

---
http://www.cochrane.org/fr/CD003448
2011
false
true
false
United Kingdom
France
quaternary ammonium compounds
review of literature
french abstract
methylnaltrexone
palliative care
constipation
laxatives

---
http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14087a-fra.php
http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2010/14622a-fra.php
2010
Canada
English
French
constipation
methylnaltrexone
naltrexone
methylnaltrexone bromide
narcotic antagonists
quaternary ammonium compounds
injections, subcutaneous
Gastrointestinal perforation
intestinal perforation
pharmacovigilance note

---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Relistor_January-30-2009-fr.pdf
2009
false
Canada
French
Drug-induced constipation (disorder)
narcotic antagonists
quaternary ammonium compounds
naltrexone
receptors, opioid, mu
constipation
constipation
analgesics, opioid
injections, subcutaneous
pharmaceutical solutions
treatment outcome
terminal care
methylnaltrexone
methylnaltrexone bromide
drug evaluation

---
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17/05/2024


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