histone deacetylase inhibitors

Preferred Label : histone deacetylase inhibitors;

MeSH definition : Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.;

MeSH synonym : deacetylase inhibitors, histone; HDAC inhibitors; histone deacetylase inhibitor; inhibitors, histone deacetylase; deacetylase inhibitor, histone; inhibitor, histone deacetylase; inhibitors, HDAC; HDAC Inhibitor; Inhibitor, HDAC;

Wikipedia link : https://en.wikipedia.org/wiki/Histone deacetylase inhibitor;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D056572;

UMLS CUI

C1512474;

ATC code(s)
- Histone deacetylase (HDAC) inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Histone deacetylase (HDAC) inhibitors [ATC Code]
- Histone deacetylase inhibitor (disposition) [SNOMED CT concept]
- Product containing histone deacetylase inhibitor (product) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Histone Deacetylase Inhibitor [NCIt concept]
- Substance with histone deacetylase inhibitor mechanism of action (substance) [SNOMED CT concept]
Indexing information
- 2-((1-(3-fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide [MeSH Supplementary Concept]
- 2-(2-(3,3-dimethylbutanamido)-3-methylpentanoyl)-7-(2-(hydroxyamino)-2-oxoethoxy)-N-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide [MeSH Supplementary Concept]
- 2-(6-(((6-fluoroquinolin-2-yl)methyl)amino)bicyclo(3.1.0)hex-3-yl)-N-hydroxypyrimidine-5-carboxamide [MeSH Supplementary Concept]
- 3-(1-benzenesulfonyl-1H-indol-5-yl)-N-hydroxyacrylamide [MeSH Supplementary Concept]
- 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide [MeSH Supplementary Concept]
- 3-(2-(4-pyridin-4-yl)benzyl-1-oxoisoindolin-6-yl)-N-hydroxyacrylamide [MeSH Supplementary Concept]
- 3-(2-(4-quinolin-3-yl)benzyl-1-oxoisoindolin-6-yl)-N-hydroxy-acrylamide [MeSH Supplementary Concept]
- 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide [MeSH Supplementary Concept]
- 4-(2,2-dimethyl-4-phenylbutyrylamino)-N-hydroxybenzamide [MeSH Supplementary Concept]
- 5-(6-dimethylamino-2-methyl-3-oxo-2,3-dihydro-benzofuran-2-yl)-4-methyl-penta-2,4-dienoic acid hydroxamide [MeSH Supplementary Concept]
- 5-phenylcarbamoylpentyl selenocyanide [MeSH Supplementary Concept]
- 6-(3-hydroxy-3-methylbutyl)-2'-(7-hydroxy-3,7-dimethyloct-3-enyl)-3',4',7-trimethoxyflavanone [MeSH Supplementary Concept]
- 6-(4-chlorophenylsulfanyl)-2,4-hexadienoic acid hydroxyamide [MeSH Supplementary Concept]
- BRD73954 [MeSH Supplementary Concept]
- CHR 2845 [MeSH Supplementary Concept]
- CPUYS707 [MeSH Supplementary Concept]
- CUDC-907 [MeSH Supplementary Concept]
- JAHA-PIP-delta [MeSH Supplementary Concept]
- Ky-2 cyclic peptide [MeSH Supplementary Concept]
- MC1293 [MeSH Supplementary Concept]
- MC1568 [MeSH Supplementary Concept]
- MC1575 [MeSH Supplementary Concept]
- MI-192 [MeSH Supplementary Concept]
- N-hydroxy-2-(1-phenylcycloproylamino)pyrimidine-5-carboxamide [MeSH Supplementary Concept]
- N-hydroxy-3-(4-(((2-(2-(1-hydroxy-1-methylethyl)-1H-indol-3-yl)ethyl)isopropylamino)methyl)phenyl)acrylamide [MeSH Supplementary Concept]
- N-hydroxy-3-(4-((2-(2-methylpyrazolo(1,5-a)pyridin-3-yl)ethylamino)methyl)phenyl)acrylamide [MeSH Supplementary Concept]
- N-hydroxy-6-(((adamantan-1-ylamino)carbonyl)amino)hexamide [MeSH Supplementary Concept]
- N1-(3-(dimethylamino)propyl)-N8-hydroxy-2-((naphthalene-1-loxy)methyl)oct-2-enediamide [MeSH Supplementary Concept]
- N1-4-((biphenylsulphonyl)amino)phenyl-2-amino-3-phenyl-propionamide [MeSH Supplementary Concept]
- N1-hydroxy-N8-(4-(phenylamino)phenyl)octanediamide [MeSH Supplementary Concept]
- N8-hydroxy-2-(1H-indole-2-carboxamido)-N1-(quinolin-8-yl)octanediamide [MeSH Supplementary Concept]
- SAHA-PIP-delta [MeSH Supplementary Concept]
- SB939 compound [MeSH Supplementary Concept]
- UCL67022 [MeSH Supplementary Concept]
- YM753 compound [MeSH Supplementary Concept]
- apicidin F [MeSH Supplementary Concept]
- bis(5-phenylcarbamoylpentyl) diselenide [MeSH Supplementary Concept]
- givinostat [MeSH Supplementary Concept]
- jay amin hydroxamic acid [MeSH Supplementary Concept]
- kendine 91 [MeSH Supplementary Concept]
- kendine 92 [MeSH Supplementary Concept]
- methyl-4-(phenylthio)butanoate [MeSH Supplementary Concept]
- octanedioic acid (1-(3-azido-5-azidomethylbenzyl)-1H-pyrazol-4-yl)amide hydroxyamide [MeSH Supplementary Concept]
- refrofractamide A [MeSH Supplementary Concept]
- ricolinostat [MeSH Supplementary Concept]
- santacruzamate A [MeSH Supplementary Concept]
- spiruchostatin D [MeSH Supplementary Concept]
- streptosetin A [MeSH Supplementary Concept]
- thailandepsin A [MeSH Supplementary Concept]
MeSH Descriptor(s) used for indexing
- histone deacetylases [MeSH Descriptor]
Record concept(s)
- histone deacetylase inhibitors [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- 3-(1-cinnamyl-1H-1,2,3-triazol-4-yl)-N-hydroxyacrylamide [MeSH Supplementary Concept]
- 3-(1-methyl-4-phenylacetyl-1H-2-pyrrolyl)-N-hydroxypropenamide [MeSH Supplementary Concept]
- 3-(3-(3-(3-chlorophenyl)-3-oxopropenyl)-1-methylpyrrol-2-yl)propenoic hydroxamic acid [MeSH Supplementary Concept]
- 3-(3-(benzofuran-2-carbonyl)phenyl)-N-hydroxyacrylamide [MeSH Supplementary Concept]
- 4-(3-(hydroxyamino)-3-oxoprop-1-enyl)-N-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)benzamide [MeSH Supplementary Concept]
- 4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [MeSH Supplementary Concept]
- 4-dimethylamino-N-(4-(2-hydroxycarbamoylvinyl)benzyl)benzamide [MeSH Supplementary Concept]
- 4-dimethylamino-N-(5-(2-mercaptoacetylamino)pentyl)benzamide [MeSH Supplementary Concept]
- 5-((6-(3-chlorophenyl)-4-oxo-3H-pyrimidin-2-yl)thio)pentanoic hydroxamic acid [MeSH Supplementary Concept]
- 5-nitroso-8-quinolinol [MeSH Supplementary Concept]
- 7-(4-(4-cyanophenyl)phenoxy)heptanohydroxamic acid [MeSH Supplementary Concept]
- 7-phenyl-2,4,6-heptatrienoylhydroxamic acid [MeSH Supplementary Concept]
- A452 compound [MeSH Supplementary Concept]
- ACS2 compound [MeSH Supplementary Concept]
- ACS33 compound [MeSH Supplementary Concept]
- AES-135 [MeSH Supplementary Concept]
- CAY10603 [MeSH Supplementary Concept]
- CKD-506 [MeSH Supplementary Concept]
- CKD-581 [MeSH Supplementary Concept]
- CRA 026440 [MeSH Supplementary Concept]
- HKI 46F08 [MeSH Supplementary Concept]
- KBH A42 [MeSH Supplementary Concept]
- LG325 [MeSH Supplementary Concept]
- LMK-235 [MeSH Supplementary Concept]
- N-(2-aminophenyl)-4-((benzyl(2-hydroxyethyl)amino)methyl) benzamide [MeSH Supplementary Concept]
- N-(4-(2-hydroxycarbamoylvinyl)benzyl)-4-pyrrolidin-1-ylbenzamide [MeSH Supplementary Concept]
- N-hydroxy-3-(2-oxo-1-phenethyl-1,2,5,6-tetrahydropyridin-3-yl)propanamide [MeSH Supplementary Concept]
- N-hydroxy-3-(3-(1H-indole-2-carbonyl)phenyl)acrylamide [MeSH Supplementary Concept]
- N-hydroxy-4-(3-methyl-2-phenylbutyrylamino)benzamide [MeSH Supplementary Concept]
- N-hydroxy-4-(4-phenylbutyrylamino)benzamide [MeSH Supplementary Concept]
- N-hydroxy-7-(2-naphthylthio)heptanamide [MeSH Supplementary Concept]
- N1-(2-aminophenyl)-N4-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)terephthalamide [MeSH Supplementary Concept]
- N1-(2-aminophenyl)-N7-phenylheptanediamide [MeSH Supplementary Concept]
- N1-(2-aminophenyl)-N8-phenyloctanediamide [MeSH Supplementary Concept]
- N2-(2-aminophenyl)-N5-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)thiophene-2,5-dicarboxamide [MeSH Supplementary Concept]
- O-n-butanoyl-2,3-O-isopropylidenemannofuranoside [MeSH Supplementary Concept]
- Panobinostat [MeSH Descriptor]
- R 306465 [MeSH Supplementary Concept]
- SD-0203 [MeSH Supplementary Concept]
- SD-2007 [MeSH Supplementary Concept]
- SW-100 [MeSH Supplementary Concept]
- Vorinostat [MeSH Descriptor]
- WMJ-8-B [MeSH Supplementary Concept]
- WT161 [MeSH Supplementary Concept]
- abexinostat [MeSH Supplementary Concept]
- animacroxam [MeSH Supplementary Concept]
- apicidin [MeSH Supplementary Concept]
- azelaic bishydroxamic acid [MeSH Supplementary Concept]
- belinostat [MeSH Supplementary Concept]
- bexarotene hydroxamic acid [MeSH Supplementary Concept]
- butyroyloxymethyl 4-phenylbutyrate [MeSH Supplementary Concept]
- carboxycinnamic acid bishydroxamide [MeSH Supplementary Concept]
- citarinostat [MeSH Supplementary Concept]
- cyclic hydroxamic acid-containing peptide 1 [MeSH Supplementary Concept]
- entinostat [MeSH Supplementary Concept]
- givinostat hydrochloride [MeSH Supplementary Concept]
- marbostat-100 [MeSH Supplementary Concept]
- metacept-1 [MeSH Supplementary Concept]
- mocetinostat [MeSH Supplementary Concept]
- ricolinostat [MeSH Supplementary Concept]
- romidepsin [MeSH Supplementary Concept]
- santacruzamate A [MeSH Supplementary Concept]
- scriptaid [MeSH Supplementary Concept]
- scriptide [MeSH Supplementary Concept]
- spiruchostatin B [MeSH Supplementary Concept]
- tacedinaline [MeSH Supplementary Concept]
- thioisobutyric acid S-(6-(4-phenyl-2-thiazolylcarbamoyl)hexyl) ester [MeSH Supplementary Concept]
- trapoxin A [MeSH Supplementary Concept]
- trichostatin A [MeSH Supplementary Concept]
- triciferol [MeSH Supplementary Concept]
- tubacin [MeSH Supplementary Concept]
UMLS correspondences (same concept)
- Histone Deacetylase Inhibitor [NCIt concept]
- Product containing histone deacetylase inhibitor (product) [SNOMED CT concept]
- Substance with histone deacetylase inhibitor mechanism of action (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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