romidepsin - CISMeF

Preferred Label : romidepsin;

MeSH note : a bicyclic depsipeptide; isolated from Chromobacterium violaceum; structure given in first source;

CISMeF synonym : 7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo(8,7,6)tricos-16-ene-3,6,9,19,22-pentanone; FK228; FR 901228; istodax; astella pharma brand of romidepsin;

MeSH synonym : L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))-;

MeSH hyponym : FR-901228; FR901228;

MeSH CAS label : L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))-;

MeSH Related Number : 128517-07-7;

Registry Number MeSH : 128517-07-7;

Is substance : O;

UNII : CX3T89XQBK;

InChIKey : OHRURASPPZQGQM-GCCNXGTGSA-N;

Details

Origin ID

C087123;

UMLS CUI

C1527027;

ATC code(s)
- romidepsin [ATC Code]
Currated CISMeF NLP mapping
- Romidepsin [NCIt concept]
- Romidepsin (substance) [SNOMED CT concept]
MeSH term(s) associated for indexing
- depsipeptides [MeSH Descriptor]
Pharmacological action(s)
- antibiotics, antineoplastic [MeSH Descriptor]
- histone deacetylase inhibitors [MeSH Descriptor]
Record concept(s)
- FK228 [MeSH concept]
- FR 901228 [MeSH concept]
- istodax [MeSH concept]
- romidepsin [MeSH concept]
See also inter- (CISMeF)
- Product containing romidepsin (medicinal product) [SNOMED CT concept]
- depsipeptides [IUPAC Term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing romidepsin (medicinal product) [SNOMED CT concept]
- Romidepsin [NCIt concept]
- Romidepsin (substance) [SNOMED CT concept]
- romidepsin [ATC Code]

Keyword's position in hierarchy(ies) :

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