leukocyte l1 antigen complex

Preferred Label : leukocyte l1 antigen complex;

MeSH definition : A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.;

MeSH synonym : antigen l1, myelomonocytic; calcium binding myeloid protein p8,14; calcium-binding myeloid protein p8,14; calgranulin; calprotectin; l1 antigen; l1 protein, leukocyte; migratory inhibitory factor related protein mrp; migratory inhibitory factor-related protein mrp; myelomonocytic antigen l1; 27e10 antigen; antigen, l1; antigen, 27e10; leukocyte l1 protein;

Is substance : O;

Details

Origin ID

D039841;

UMLS CUI

C0950624;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Calprotectin Measurement [NCIt concept]
- Protein S100-A8 [NCIt concept]
- S100 calcium-binding protein a8 [OMIM gene]
- S100 calcium-binding protein a9 [OMIM gene]
Currated CISMeF NLP mapping
- Calprotectin [NCIt concept]
- Calprotectin [LOINC component]
- Calprotectin (substance) [SNOMED CT concept]
- calprotectin [COVID-19 Thesaurus concept]
- calprotectin [EMDN type]
- calprotectin [medical devices type]
Record concept(s)
- leukocyte L1 antigen complex [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Calprotectin [NCIt concept]
- Calprotectin [LOINC component]
- Calprotectin (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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