troponin t - CISMeF

Preferred Label : troponin t;

MeSH definition : One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.; A TROPONIN complex subunit that binds to TROPOMYOSIN. There are three troponin T subtypes: troponin T1, T2 and T3. Troponin T2 is cardiac-specific whereas troponin T2 and T3 are skeletal subtypes. Troponin T2 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin T2 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.;

MeSH synonym : Troponin-T;

CISMeF synonym : t, troponin; T2, troponin; T1, troponin;

DeCS synonym : Troponin T3;

MeSH hyponym : troponin T2; troponin T1;

MeSH annotation : TROPONIN C & TROPONIN I are also available;

Wikipedia link : https://en.wikipedia.org/wiki/Troponin t;

Is substance : O;

Details

Origin ID

D020107;

UMLS CUI

C0077404;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Troponin [FMA entity]
- Troponin [MedDRA Preferred Term]
- Troponin (substance) [SNOMED CT concept]
- Troponin I [MedDRA Preferred Term]
- Troponin T Measurement [NCIt concept]
- Troponin t1, skeletal, slow [OMIM gene]
- troponin T1, slow skeletal type [HGNC gene]
- troponin c [SNOMED Notion]
- troponin i [SNOMED Notion]
- troponin, nos [SNOMED Notion]
Currated CISMeF NLP mapping
- Troponin T [MedDRA Preferred Term]
- Troponin T [NCIt concept]
- Troponin T (substance) [SNOMED CT concept]
- Troponin-T [FMA entity]
- troponin t [SNOMED Notion]
Record concept(s)
- Troponin T3 [MeSH concept]
- troponin T [MeSH concept]
- troponin T1 [MeSH concept]
- troponin T2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TNNT2 protein, human [MeSH Supplementary Concept]
- TNNT3 protein, human [MeSH Supplementary Concept]
- Tnnt2 protein, mouse [MeSH Supplementary Concept]
- Tnnt2 protein, rat [MeSH Supplementary Concept]
- Tnnt3b protein, zebrafish [MeSH Supplementary Concept]
- cardiomyopathy, familial hypertrophic, 2 [MeSH Supplementary Concept]
- phosphotroponin [MeSH Supplementary Concept]
- tnnt2a protein, zebrafish [MeSH Supplementary Concept]
See also
- cardiomyopathy, hypertrophic, familial [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Troponin T [LOINC component]
- Troponin T [NCIt concept]
- Troponin T (substance) [SNOMED CT concept]
- Troponin-T [FMA entity]
- troponin t [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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