troponin i - CISMeF

Preferred Label : troponin i;

MeSH definition : One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.; A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.;

MeSH synonym : Troponin-I;

DeCS synonym : Troponin I3; Troponin I1; Troponin I2;

MeSH annotation : a muscle protein; /biosyn /physiol permitted; TROPONIN C & TROPONIN T are also available; TROPONIN C & TROPONIN T are also available;

Wikipedia link : https://en.wikipedia.org/wiki/Troponin i;

Is substance : O;

Details

Origin ID

D019210;

UMLS CUI

C0077401;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Troponin [FMA entity]
- Troponin [MedDRA Preferred Term]
- Troponin (substance) [SNOMED CT concept]
- Troponin I Measurement [NCIt concept]
- Troponin T [MedDRA Preferred Term]
- Troponin T/I [ICHI extension code]
- troponin (t + i) [medical devices type]
- troponin I2, fast skeletal type [HGNC gene]
- troponin c [SNOMED Notion]
- troponin t [SNOMED Notion]
- troponin, nos [SNOMED Notion]
Currated CISMeF NLP mapping
- Troponin I [MedDRA Preferred Term]
- Troponin I [NCIt concept]
- Troponin I (substance) [SNOMED CT concept]
- Troponin-I [FMA entity]
- troponin i [SNOMED Notion]
Record concept(s)
- Troponin I1 [MeSH concept]
- Troponin I2 [MeSH concept]
- Troponin I3 [MeSH concept]
- troponin I [MeSH concept]
Related MeSH Supplementary Concept(s)
- TNNI1 protein, human [MeSH Supplementary Concept]
- TNNI2 protein, human [MeSH Supplementary Concept]
- TNNI3 protein, human [MeSH Supplementary Concept]
- Tnni1 protein, rat [MeSH Supplementary Concept]
- troponin I (104-115) [MeSH Supplementary Concept]
- troponin I, C elegans [MeSH Supplementary Concept]
- wupA protein, Drosophila [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Troponin I [NCIt concept]
- Troponin I (substance) [SNOMED CT concept]
- Troponin-I [FMA entity]
- troponin i [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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