Preferred Label : endodermal sinus tumor;
MeSH definition : An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic
structures of the early embryo. It is the most common malignant germ cell tumor found
in children. It is characterized by a labyrinthine glandular pattern of flat epithelial
cells and rounded papillary processes with a central capillary (Schiller-Duval body).
The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor
was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice
of Oncology, 3d ed, p1189);
MeSH synonym : tumor, endodermal sinus; tumors, endodermal sinus; yolk sac tumor; tumor, yolk sac; tumors, yolk sac; yolk sac tumors; endodermal sinus tumors;
MeSH annotation : /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord
organ/neopl term (IM); coordinate with precoordinated organ/neoplasm term;
Wikipedia link : https://en.wikipedia.org/wiki/Endodermal sinus tumor;
Origin ID : D018240;
UMLS CUI : C0014145;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
DO Cross reference
ORDO relation(s)
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic
structures of the early embryo. It is the most common malignant germ cell tumor found
in children. It is characterized by a labyrinthine glandular pattern of flat epithelial
cells and rounded papillary processes with a central capillary (Schiller-Duval body).
The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor
was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice
of Oncology, 3d ed, p1189)
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=876
2014
false
true
false
France
scientific and technical information
endodermal sinus tumor
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http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=252006
2011
France
scientific and technical information
endoderm
endodermal sinus tumor
nervous system
brain neoplasms
---