Preferred Label : endodermal sinus tumor;
MeSH definition : An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic
structures of the early embryo. It is the most common malignant germ cell tumor found
in children. It is characterized by a labyrinthine glandular pattern of flat epithelial
cells and rounded papillary processes with a central capillary (Schiller-Duval body).
The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor
was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice
of Oncology, 3d ed, p1189);
MeSH synonym : tumor, endodermal sinus; tumors, endodermal sinus; yolk sac tumor; tumor, yolk sac; tumors, yolk sac; yolk sac tumors; endodermal sinus tumors;
MeSH annotation : /blood supply /chem /second /secret /ultrastruct permitted; coord IM with precoord
organ/neopl term (IM); coordinate with precoordinated organ/neoplasm term;
Wikipedia link : https://en.wikipedia.org/wiki/Endodermal sinus tumor;
Origin ID : D018240;
UMLS CUI : C0014145;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
DO Cross reference
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic
structures of the early embryo. It is the most common malignant germ cell tumor found
in children. It is characterized by a labyrinthine glandular pattern of flat epithelial
cells and rounded papillary processes with a central capillary (Schiller-Duval body).
The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor
was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice
of Oncology, 3d ed, p1189)
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=876
2014
false
true
false
France
scientific and technical information
endodermal sinus tumor
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http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=252006
2011
France
scientific and technical information
endoderm
endodermal sinus tumor
nervous system
brain neoplasms
---