Yolk Sac Tumor

Preferred Label : Yolk Sac Tumor;

NCIt synonyms : Yolk Sac Tumour Site Unspecified;

NCIt related terms : Endodermal sinus tumor; Yolk Sac Neoplasm; Endodermal Sinus Neoplasm; Yolk Sac Tumor Site Unspecified; Carcinoma, Yolk Sac; YOLK SAC TUMOR, MALIGNANT;

NCIt definition : A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.;

Alternative definition : CDISC: A non-seminomatous malignant germ cell tumor composed of primitive germ cells and which produce an eosinophilic substance (alpha-fetoprotein).;

Neoplastic status : Malignant;

ICD-O code : 9071/3;

Details

Origin ID

C3011;

UMLS CUI

C0014145;

Automatic exact mappings (from CISMeF team)
- Endodermal sinus tumor [ICD-9 code]
- Endodermal sinus tumour, unspecified site, male [ICD-11 More detail]
- Testicular germ cell tumor [OMIM Phenotype]
Currated CISMeF NLP mapping
- Endodermal sinus tumor [PASCAL descriptor]
- Endodermal sinus tumor (morphologic abnormality) [SNOMED CT concept]
- Yolk sac tumor [ICD-O code]
- Yolk sac tumor [ORDO Disease]
- Yolk sac tumour [ICD-11 Extension code]
- endodermal sinus tumor [DO Concept]
- endodermal sinus tumor [MeSH Descriptor]
- endodermal sinus tumor [MeSH concept]
- endodermal sinus tumor [SNOMED Notion]
- yolk sac tumor [Disease (Nov.)]
- yolk sac tumor [Radlex concept]
DO Cross reference
- endodermal sinus tumor [DO Concept]
Disease excludes abnormal cell
- Neoplastic Sex Cord-Stromal Cell [NCIt concept]
Disease may have findings
- Alpha Fetoprotein Increased [NCIt concept]
- Cytoplasmic Hyaline Globules Present [NCIt concept]
- Schiller-Duval Body [NCIt concept]
False automatic mappings
- Yolk sac tumor (disorder) [SNOMED CT concept]
- Yolk sac tumour site unspecified [MedDRA Preferred Term]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Endodermal sinus tumor [PASCAL descriptor]
- Endodermal sinus tumor (morphologic abnormality) [SNOMED CT concept]
- Endodermal sinus tumor site unspecified [MedDRA LLT]
- Endodermal sinus tumour site unspecified [MedDRA LLT]
- Orchioblastoma [PASCAL descriptor]
- Yolk sac tumor [ORDO Disease]
- Yolk sac tumor [ICD-O code]
- Yolk sac tumor (disorder) [SNOMED CT concept]
- Yolk sac tumour [ICD-11 Extension code]
- Yolk sac tumour site unspecified [MedDRA Preferred Term]
- endodermal sinus tumor [DO Concept]
- endodermal sinus tumor [MeSH concept]
- endodermal sinus tumor [MeSH Descriptor]
- endodermal sinus tumor [SNOMED Notion]
- yolk sac tumor [Radlex concept]
- yolk sac tumor [Disease (Nov.)]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- CTS-API Disease Main Type Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- Clinical Trials Search-Application Programming Interface Disease Category Terminology [NCIt concept]
- GCT Authorized Value Terminology [NCIt concept]
- GCT Histology Table [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Malignant Germinomatous Cells Present [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Germ Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Mitotic Activity [NCIt concept]
disease_has_normal_cell_origin
- Germ Cell [NCIt concept]
disease_has_normal_tissue_origin
- Germinal Layer [NCIt concept]
human_disease_maps_to_eo_disease
- Yolk Sac Tumour of the Mouse Nervous System [NCIt concept]
neoplasm_has_special_category
- Solid Neoplasm [NCIt concept]

Keyword's position in hierarchy(ies) :

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