Definition : An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic
structures of the early embryo. It is the most common malignant germ cell tumor found
in children. It is characterized by a labyrinthine glandular pattern of flat epithelial
cells and rounded papillary processes with a central capillary (Schiller-Duval body).
The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor
was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice
of Oncology, 3d ed, p1189) [MeSH];
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic
structures of the early embryo. It is the most common malignant germ cell tumor found
in children. It is characterized by a labyrinthine glandular pattern of flat epithelial
cells and rounded papillary processes with a central capillary (Schiller-Duval body).
The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor
was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice
of Oncology, 3d ed, p1189) [MeSH]