Preferred Label : lupus coagulation inhibitor;
MeSH definition : An antiphospholipid antibody found in association with systemic lupus erythematosus
(LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other
diseases as well as in healthy individuals. In vitro, the antibody interferes with
the conversion of prothrombin to thrombin and prolongs the partial thromboplastin
time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the
larger veins and arteries. It further causes obstetrical complications, including
fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic
complications.; An antiphospholipid antibody found in association with a variety of diseases (e.g.,
SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME) as well as in healthy
individuals. In vitro, the antibody interferes with the conversion of prothrombin
to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant
effect resulting in thrombosis mainly in the larger veins and arteries. It further
causes obstetrical complications, including fetal death and spontaneous abortion,
as well as a variety of hematologic and neurologic complications.;
MeSH synonym : anticoagulant, lupus; inhibitor, lupus coagulation; coagulation inhibitor, lupus; lupus anticoagulant; Lupus Anticoagulant Autoantibody; Anticoagulant Autoantibody, Lupus; Autoantibody, Lupus Anticoagulant; Lupus Anticoagulant Autoantibodies;
MeSH annotation : DF: LUPUS COAG INHIB;
Wikipedia link : https://en.wikipedia.org/wiki/Lupus coagulation inhibitor;
Is substance : O;
Origin ID : D016682;
UMLS CUI : C0085240;
Allowable qualifiers
Automatic exact mappings (from CISMeF team)
Pharmacological action(s)
Record concept(s)
See also
See also (suggested by CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
An antiphospholipid antibody found in association with systemic lupus erythematosus
(LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other
diseases as well as in healthy individuals. In vitro, the antibody interferes with
the conversion of prothrombin to thrombin and prolongs the partial thromboplastin
time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the
larger veins and arteries. It further causes obstetrical complications, including
fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic
complications.
An antiphospholipid antibody found in association with a variety of diseases (e.g.,
SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME) as well as in healthy
individuals. In vitro, the antibody interferes with the conversion of prothrombin
to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant
effect resulting in thrombosis mainly in the larger veins and arteries. It further
causes obstetrical complications, including fetal death and spontaneous abortion,
as well as a variety of hematologic and neurologic complications.
https://dumas.ccsd.cnrs.fr/dumas-02091489/document
2018
France
dissertations, academic
adoption
anticoagulant, nos
Biology
asthenia
patient care management
Lupus
biology
adoption, nos
biology
lupus coagulation inhibitor
anticoagulants
anticoagulants
---
http://www.cochrane.org/fr/CD002859
2012
false
true
false
United Kingdom
France
treatment outcome
pregnancy
review of literature
french abstract
antibodies, antiphospholipid
abortion, spontaneous
lupus coagulation inhibitor
---
http://www.has-sante.fr/portail/jcms/c_1009982/biologie-des-anomalies-de-lhemostase-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084558/biologie-anomalie-hemostase-t1-temps-de-saignement-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084559/biologie-anomalie-hemostase-t2-thrombine-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084560/biologie-anomalie-hemostase-t3-tap-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084561/biologie-anomalie-hemostase-t4-ac-anti-f4p-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084562/biologie-anomalie-hemostase-t5-inhibiteurs-fah-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084563/biologie-anomalie-hemostase-t6-al-rapport-d-evaluation
http://www.has-sante.fr/portail/jcms/c_1084564/biologie-anomalie-hemostase-t7-mutations-fii-et-fv-rapport-d-evaluation
2011
true
France
French
health technology assessment
hemostatic disorders
bleeding time
thrombin time
platelet aggregation
platelet factor 4
factor VIII
lupus coagulation inhibitor
factor v
prothrombin
factor V leiden
---
http://www.has-sante.fr/portail/display.jsp?id=c_474508
2006
true
France
French
antiphospholipid syndrome
antiphospholipid syndrome
lupus coagulation inhibitor
assessment of professional actions
---