lupus coagulation inhibitor

Preferred Label : lupus coagulation inhibitor;

MeSH definition : An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.; An antiphospholipid antibody found in association with a variety of diseases (e.g., SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME) as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.;

MeSH synonym : anticoagulant, lupus; inhibitor, lupus coagulation; coagulation inhibitor, lupus; lupus anticoagulant; Lupus Anticoagulant Autoantibody; Anticoagulant Autoantibody, Lupus; Autoantibody, Lupus Anticoagulant; Lupus Anticoagulant Autoantibodies;

MeSH annotation : DF: LUPUS COAG INHIB;

Wikipedia link : https://en.wikipedia.org/wiki/Lupus coagulation inhibitor;

Is substance : O;

Details

Origin ID

D016682;

UMLS CUI

C0085240;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Lupus Anticoagulant Antibody [NCIt concept]
- Lupus anticoagulant [HPO term]
- Lupus anticoagulant [LOINC component]
- Lupus anticoagulant [MedDRA LLT]
- Lupus anticoagulant (substance) [SNOMED CT concept]
- Lupus anticoagulant assay (procedure) [SNOMED CT concept]
- Lupus anticoagulant disorder (disorder) [SNOMED CT concept]
- lupus anticoagulant [EMDN type]
- lupus anticoagulant, nos [SNOMED Notion]
- lupus coagulation inhibitor [Blood Transfusion thesaurus concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- lupus coagulation inhibitor [MeSH concept]
See also
- antiphospholipid syndrome [MeSH Descriptor]
- lupus erythematosus, systemic [MeSH Descriptor]
See also (suggested by CISMeF)
- circulating anticoagulants [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Lupus anticoagulant [LOINC component]
- Lupus anticoagulant (substance) [SNOMED CT concept]
- lupus anticoagulant, nos [SNOMED Notion]

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