motor neuron disease

Preferred Label : motor neuron disease;

MeSH definition : Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089);

MeSH synonym : motor system disease; neuron disease, motor; motor neuron diseases; neuron diseases, motor; motor system diseases;

Wikipedia automatic translation : Amyotrophic lateral sclerosis;

MeSH hyponym : lateral sclerosis; motor neuron disease, secondary; familial motor neuron disease; motor neuron disease, lower; motor neuron disease, upper; anterior horn cell disease; Motor Neuron Disease, Familial; Lateral Scleroses; Scleroses, Lateral; Sclerosis, Lateral; Primary Lateral Sclerosis; Lateral Scleroses, Primary; Lateral Sclerosis, Primary; Primary Lateral Scleroses; Scleroses, Primary Lateral; Sclerosis, Primary Lateral; Upper Motor Neuron Disease; Secondary Motor Neuron Disease; Lower Motor Neuron Disease;

MeSH annotation : GEN or unspecified; prefer specifics; general or unspecified; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Amyotrophic lateral sclerosis;

Details

Origin ID

D016472;

UMLS CUI

C0085084;

Allowable qualifiers
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemically induced [MeSH Qualifier]
- classification [MeSH Qualifier]
- complications [MeSH Qualifier]
- congenital [MeSH Qualifier]
- diagnosis [MeSH Qualifier]
- diagnostic imaging [MeSH Qualifier]
- diet therapy [MeSH Qualifier]
- drug therapy [MeSH Qualifier]
- economics [MeSH Qualifier]
- embryology [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- epidemiology [MeSH Qualifier]
- ethnology [MeSH Qualifier]
- etiology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- mortality [MeSH Qualifier]
- nursing [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiopathology [MeSH Qualifier]
- prevention and control [MeSH Qualifier]
- psychology [MeSH Qualifier]
- radiotherapy [MeSH Qualifier]
- rehabilitation [MeSH Qualifier]
- surgery [MeSH Qualifier]
- therapy [MeSH Qualifier]
- urine [MeSH Qualifier]
- veterinary [MeSH Qualifier]
- virology [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Abnormal anterior horn cell morphology [HPO term]
- Abnormal lower motor neuron morphology [HPO term]
- Anterior horn cell disease [ICD-9 code]
- Anterior horn cell disease [MedDRA LLT]
- Anterior horn cell disease (disorder) [SNOMED CT concept]
- Anterior horn cell disease NOS [MedDRA LLT]
- Hereditary motor neuron disease (disorder) [SNOMED CT concept]
- Lower motor neuron disease (disorder) [SNOMED CT concept]
- Upper motor neuron disease (disorder) [SNOMED CT concept]
- anterior horn cell disease [DO Concept]
- anterior horn cell disease, nos [SNOMED Notion]
- familial motor neuron disease, nos [SNOMED Notion]
- lateral sclerosis [DO Concept]
- lower motor neuron disease, nos [SNOMED Notion]
- upper motor neuron disease, nos [SNOMED Notion]
Currated CISMeF NLP mapping
- Motor Neuron Disease [NCIt concept]
- Motor neuron disease [PASCAL descriptor]
- Motor neuron disease [ICD-10 Sub-category]
- Motor neuron disease [ICD-11 Category]
- Motor neuron disease [ICD-10 Sub-category (who)]
- Motor neuron disease [ICD-9 code]
- Motor neuron disease [ORDO Disease]
- Motor neuron disease [MedDRA LLT]
- Motor neuron disease (disorder) [SNOMED CT concept]
- Motor neurone disease [MedDRA Preferred Term]
- Motor neurone diseases [MedDRA High Level Term]
- Primary lateral sclerosis [ICD-11 Subcategory]
- Primary lateral sclerosis [ICD-9 code]
- Primary lateral sclerosis [ORDO Disease]
- Primary lateral sclerosis [MedDRA LLT]
- Primary lateral sclerosis (disorder) [SNOMED CT concept]
- Primary lateral sclerosis, juvenile [OMIM Phenotype]
- motor neuron disease [DO Concept]
- motor neuron disease [Disease (Nov.)]
- motor neuron disease, nos [SNOMED Notion]
- neurological disease other [ICPC-2 Rubric]
- primary lateral sclerosis [SNOMED Notion]
DO Cross reference
- anterior horn cell disease [DO Concept]
- lateral sclerosis [DO Concept]
- motor neuron disease [DO Concept]
HPO term
- Abnormal anterior horn cell morphology [HPO term]
Manual BTNT mappings - CISMeF
- Acquired motor neuron disease [ORDO Disease]
- Genetic motor neuron disease [ORDO Disease]
Manual NTBT mappings (CISMeF)
- Genetic neurodegenerative disease [ORDO Disease]
- Rare neurodegenerative disease [ORDO Disease]
ORDO relation(s)
- Motor neuron disease [ORDO Disease]
Record concept(s)
- anterior horn cell disease [MeSH concept]
- familial motor neuron disease [MeSH concept]
- lateral sclerosis [MeSH concept]
- motor neuron disease [MeSH concept]
- motor neuron disease, lower [MeSH concept]
- motor neuron disease, secondary [MeSH concept]
- motor neuron disease, upper [MeSH concept]
Related MeSH Supplementary Concept(s)
- lethal arthrogryposis with anterior horn cell disease [MeSH Supplementary Concept]
- motor neuron disease with dementia and ophthalmoplegia [MeSH Supplementary Concept]
- neuropathy, hereditary sensorimotor, with upper motor neuron, visual pathway and autonomic disturbance [MeSH Supplementary Concept]
- primary lateral sclerosis juvenile [MeSH Supplementary Concept]
- primary lateral sclerosis, adult, 1 [MeSH Supplementary Concept]
See also
- motor neurons [MeSH Descriptor]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Motor Neuron Disease [NCIt concept]
- Motor neuron disease [ICD-9 code]
- Motor neuron disease [MedDRA LLT]
- Motor neuron disease [ICD-10 Sub-category]
- Motor neuron disease [ORDO Disease]
- Motor neuron disease [PASCAL descriptor]
- Motor neuron disease [ICD-11 Category]
- Motor neuron disease (disorder) [SNOMED CT concept]
- Motor neurone disease [MedDRA Preferred Term]
- Motor neurone diseases [MedDRA High Level Term]
- Primary lateral sclerosis [ICD-11 Subcategory]
- motor neuron disease [DO Concept]
- motor neuron disease [Disease (Nov.)]
- motor neuron disease, nos [SNOMED Notion]
Validated automatic mappings to BTNT
- Familial Motor Neuron Disease [NCIt concept]
- Primary Lateral Sclerosis [NCIt concept]
- anterior horn cell disorder [Disease (Nov.)]
- primary lateral sclerosis [Disease (Nov.)]

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