Définition CISMeF : Juvenile primary lateral sclerosis (JPLS) is a very rare motor neuron disease characterized
by progressive upper motor neuron dysfunction leading to loss of the ability to walk
with wheelchair dependence, and subsequently, loss of motor speech production.;
Juvenile primary lateral sclerosis (JPLS) is a very rare motor neuron disease characterized
by progressive upper motor neuron dysfunction leading to loss of the ability to walk
with wheelchair dependence, and subsequently, loss of motor speech production.