transforming growth factor alpha

Preferred Label : transforming growth factor alpha;

MeSH definition : An EPIDERMAL GROWTH FACTOR related protein that is found in a variety of tissues including EPITHELIUM, and maternal DECIDUA. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form which binds to the EGF RECEPTOR.;

MeSH synonym : epidermal growth factor-related transforming growth factor; tgf-alpha; tgfalpha; epidermal growth factor related transforming growth factor;

Is substance : O;

Details

Origin ID

D016211;

UMLS CUI

C0040688;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Protransforming Growth Factor Alpha [NCIt concept]
- Recombinant Transforming Growth Factor-Alpha [NCIt concept]
- TGFA Gene [NCIt concept]
- Transforming Growth Factor Alpha Measurement [NCIt concept]
- Transforming growth factor alpha [LOINC component]
- Transforming growth factor, alpha [OMIM gene]
- Tumor growth factor-alpha assay (procedure) [SNOMED CT concept]
- epidermal growth factor receptor binding [GO term]
- transforming growth factor alpha [HGNC gene]
- transforming growth factor alpha [ORDO Gene]
Currated CISMeF NLP mapping
- Transforming Growth Factor Alpha [NCIt concept]
Indexing information
- spi protein, drosophila [MeSH Supplementary Concept]
Record concept(s)
- transforming growth factor alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- TGF-alpha (34-43) methyl ester, N-acetyl- [MeSH Supplementary Concept]
- TGF-alpha-like 30-kDa glycoprotein, human [MeSH Supplementary Concept]
- TGFA protein, human [MeSH Supplementary Concept]
- grk protein, Drosophila [MeSH Supplementary Concept]
- protransforming growth factor alpha [MeSH Supplementary Concept]
- shope fibroma virus growth factor [MeSH Supplementary Concept]
- streptavidin-transforming growth factor-alpha protein, recombinant [MeSH Supplementary Concept]
- transforming growth factor alpha-Pseudomonas exotoxin A (40) [MeSH Supplementary Concept]
- transforming growth factor type alpha-Pseudomonas exotoxin A [MeSH Supplementary Concept]
- transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38) [MeSH Supplementary Concept]
- transforming growth factor(alpha)-Pseudomonas exotoxin A (35) [MeSH Supplementary Concept]
- transforming growth factor-alpha (8-50) [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Transforming growth factor alpha [LOINC component]

Keyword's position in hierarchy(ies) :

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