transforming growth factor(alpha)-Pseudomonas exotoxin A (35)

Preferred Label : transforming growth factor(alpha)-Pseudomonas exotoxin A (35);

MeSH note : a recombinant form of Pseudomonas exotoxin A containing TGFalpha near its carboxyl terminus for the treatment of bladder cancer; contains a modified carboxyl-terminal sequence KDEL which increases the toxin activity by 10 to 700 fold more potent than TP40 (TGFalpha-PE40);

MeSH synonym : PE35-TGFalpha-KDEL; PE35-TGFalpha; TGFalpha-PE35;

Is substance : O;

Details

Origin ID

C081440;

UMLS CUI

C0216687;

MeSH term(s) associated for indexing
- Pseudomonas aeruginosa Exotoxin A [MeSH Descriptor]
- exotoxins [MeSH Descriptor]
- recombinant fusion proteins [MeSH Descriptor]
- transforming growth factor alpha [MeSH Descriptor]
Record concept(s)
- transforming growth factor(alpha)-Pseudomonas exotoxin A (35) [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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