Pseudomonas aeruginosa Exotoxin A

Preferred Label : Pseudomonas aeruginosa Exotoxin A;

MeSH definition : An NAD-dependent ADP-ribosyltransferase that catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD onto elongation factor 2 (EF-2) thus arresting protein synthesis. Commonly used as the toxin in immunotoxins.;

MeSH synonym : Exotoxin A, Pseudomonas; ToxA protein, Pseudomonas aeruginosa; ETA, Pseudomonas; Exotoxin A, Pseudomonas aeruginosa;

MeSH hyponym : PE40 toxin; PE38QQR;

UNII : EC 2.4.2.31;

Details

Origin ID

D000097668;

UMLS CUI

C0072544;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Pseudomonas aeruginosa exotoxin A [MeSH concept]
- recombinant truncated Pseudomonas exotoxin A, form PE38QQR [MeSH concept]
- recombinant truncated Pseudomonas exotoxin A, form PE40 [MeSH concept]
Related MeSH Supplementary Concept(s)
- transforming growth factor(alpha)-Pseudomonas aeruginosa exotoxin (38) [MeSH Supplementary Concept]
- transforming growth factor(alpha)-Pseudomonas exotoxin A (35) [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Pseudomonas aeruginosa exotoxin A [LOINC component]

Keyword's position in hierarchy(ies) :

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