genes, tumor suppressor

Preferred Label : genes, tumor suppressor;

MeSH definition : Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.;

MeSH synonym : recessive oncogenes; genes, onco-suppressor; oncogene, recessive; genes, cancer suppressor; anti oncogenes; onco-suppressor genes; anti-oncogene; antioncogenes; genes, onco suppressor; recessive oncogene; oncogenes, recessive; cancer suppressor gene; gene, onco-suppressor; onco-suppressor gene; tumor suppressor genes; antioncogene; anti-oncogenes; tumor suppressing genes; gene, tumor suppressing; genes, tumor suppressing; tumor suppressing gene; cancer suppressor genes; gene, cancer suppressor; suppressor gene, cancer; suppressor genes, cancer; gene, tumor suppressor; tumor suppressor gene; emerogenes; emerogene;

MeSH Hyperonym : growth suppressor genes; Gene, Growth Suppressor; Growth Suppressor Gene; Suppressor Gene, Growth; Suppressor Genes, Growth; Genes, Growth Suppressor;

Related MeSH term : metastasis suppressor genes; Gene, Metastasis Suppressor; Metastasis Suppressor Gene; Suppressor Gene, Metastasis; Suppressor Genes, Metastasis; Genes, Metastasis Suppressor;

MeSH annotation : Manual 24.4.4.3;

Wikipedia link : https://en.wikipedia.org/wiki/Genes, tumor suppressor;

Details

Origin ID

D016147;

UMLS CUI

C0079427;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Metastasis Suppressor Gene [NCIt concept]
Currated CISMeF NLP mapping
- Antioncogene (substance) [SNOMED CT concept]
- Tumor Suppressor Gene [NCIt concept]
- antioncogene [SNOMED Notion]
Indexing information
- BECN1 protein, human [MeSH Supplementary Concept]
- BIN1 protein, human [MeSH Supplementary Concept]
- BRINP1 protein, human [MeSH Supplementary Concept]
- Becn1 protein, mouse [MeSH Supplementary Concept]
- CDK2AP1 protein, human [MeSH Supplementary Concept]
- CYLD protein, drosophila [MeSH Supplementary Concept]
- CYLD protein, human [MeSH Supplementary Concept]
- DIRAS3 protein, human [MeSH Supplementary Concept]
- DLG1 protein, human [MeSH Supplementary Concept]
- Dlg1 protein, mouse [MeSH Supplementary Concept]
- EIPR1 protein, human [MeSH Supplementary Concept]
- ERC2-IT1 lncRNA, human [MeSH Supplementary Concept]
- FAT1 protein, human [MeSH Supplementary Concept]
- H-cadherin [MeSH Supplementary Concept]
- HIC1 protein, zebrafish [MeSH Supplementary Concept]
- HOPX protein, human [MeSH Supplementary Concept]
- Hic1 protein, mouse [MeSH Supplementary Concept]
- IFRD1 protein, human [MeSH Supplementary Concept]
- Ifrd1 protein, mouse [MeSH Supplementary Concept]
- Ifrd1 protein, rat [MeSH Supplementary Concept]
- KISS1 protein, human [MeSH Supplementary Concept]
- Kiss1 protein, rat [MeSH Supplementary Concept]
- LATS1 protein, human [MeSH Supplementary Concept]
- LLGL1 protein, human [MeSH Supplementary Concept]
- Lats1 protein, mouse [MeSH Supplementary Concept]
- MEN1 protein, human [MeSH Supplementary Concept]
- MRO protein, human [MeSH Supplementary Concept]
- Men1 protein, mouse [MeSH Supplementary Concept]
- NBL1 protein, human [MeSH Supplementary Concept]
- NKX3-1 protein, human [MeSH Supplementary Concept]
- NRSN2 protein, human [MeSH Supplementary Concept]
- Nbl1 protein, mouse [MeSH Supplementary Concept]
- Nbl1 protein, rat [MeSH Supplementary Concept]
- Nkx3-1 protein, mouse [MeSH Supplementary Concept]
- OSCP1 protein, human [MeSH Supplementary Concept]
- PYHIN1 protein, human [MeSH Supplementary Concept]
- RARRES1 protein, human [MeSH Supplementary Concept]
- RASEF protein, human [MeSH Supplementary Concept]
- RASSF3 protein, human [MeSH Supplementary Concept]
- RASSF5 protein, human [MeSH Supplementary Concept]
- RERG protein, human [MeSH Supplementary Concept]
- RPS14 protein, human [MeSH Supplementary Concept]
- Rassf3 protein, mouse [MeSH Supplementary Concept]
- SEZ6L protein, human [MeSH Supplementary Concept]
- SLC5A8 protein, human [MeSH Supplementary Concept]
- SSBP2 protein, human [MeSH Supplementary Concept]
- Smad4 protein, mouse [MeSH Supplementary Concept]
- Smad4 protein, rat [MeSH Supplementary Concept]
- TP63 protein, Xenopus [MeSH Supplementary Concept]
- TSSC1 protein, mouse [MeSH Supplementary Concept]
- TSSC2 protein, human [MeSH Supplementary Concept]
- TSSC3 protein [MeSH Supplementary Concept]
- TSSC4 protein, human [MeSH Supplementary Concept]
- Tob1 protein, mouse [MeSH Supplementary Concept]
- Tp63 protein, zebrafish [MeSH Supplementary Concept]
- Trp63 protein, mouse [MeSH Supplementary Concept]
- Tuberous Sclerosis Complex 1 Protein [MeSH Descriptor]
- Tuberous Sclerosis Complex 2 Protein [MeSH Descriptor]
- WT1 protein, xenopus [MeSH Supplementary Concept]
- brat protein, drosophila [MeSH Supplementary Concept]
- btg2 protein, zebrafish [MeSH Supplementary Concept]
- dlg1 protein, Drosophila [MeSH Supplementary Concept]
- exostosin-2 [MeSH Supplementary Concept]
- fragile histidine triad protein [MeSH Supplementary Concept]
- l(3)mbt protein, drosophila [MeSH Supplementary Concept]
- oho31 protein, drosophila [MeSH Supplementary Concept]
Metaterm(s)
- oncology [CISMeF Metaterm]
Record concept(s)
- genes, tumor suppressor [MeSH concept]
- growth suppressor genes [MeSH concept]
- metastasis suppressor genes [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDK2AP2 protein, human [MeSH Supplementary Concept]
- Doc-1r protein, mouse [MeSH Supplementary Concept]
- FAM107A protein, human [MeSH Supplementary Concept]
- ING3 protein, human [MeSH Supplementary Concept]
- PERP protein, human [MeSH Supplementary Concept]
- Plagl1 protein, mouse [MeSH Supplementary Concept]
- Plagl1 protein, rat [MeSH Supplementary Concept]
See also
- neoplasms [MeSH Descriptor]
- tumor suppressor proteins [MeSH Descriptor]
See also (suggested by CISMeF)
- genes, suppressor [MeSH Descriptor]
See also inter- (CISMeF)
- Metastasis Suppressor Gene [NCIt concept]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Antioncogene (substance) [SNOMED CT concept]
- Tumor Suppressor Gene [NCIt concept]
- antioncogene [SNOMED Notion]

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