oncogenes - CISMeF

Preferred Label : oncogenes;

MeSH definition : Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of v- before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix c- before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.;

MeSH synonym : genes, transforming; gene, transforming; transforming genes; transforming gene; oncogene;

MeSH annotation : oncogene used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual 24.4.4.3; do not confuse with GENES, NEOPLASM;

Wikipedia link : https://en.wikipedia.org/wiki/Oncogene;

Details

Origin ID

D009857;

UMLS CUI

C0029016;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cancer Gene [NCIt concept]
- Oncogenic [NCIt concept]
- Oncogenicity [NCIt concept]
Record concept(s)
- oncogenes [MeSH concept]
Related MeSH Supplementary Concept(s)
- ORF-1 protein, human herpesvirus 6 [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- oncogene proteins [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Oncogene [NCIt concept]
- Oncogene (substance) [SNOMED CT concept]
- oncogene [SNOMED Notion]

Keyword's position in hierarchy(ies) :

Main resources

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