3-Hydroxyacyl CoA dehydrogenases

Preferred Label : 3-Hydroxyacyl CoA dehydrogenases;

MeSH definition : Enzymes that reversibly catalyze the oxidation of a 3-hydroxyacyl CoA to 3-ketoacyl CoA in the presence of NAD. They are key enzymes in the oxidation of fatty acids and in mitochondrial fatty acid synthesis.;

MeSH synonym : dehydrogenases, beta-hydroxyacyl; dehydrogenases, 3-hydroxyacyl coa; beta-hydroxyacyl dehydrogenases; coa dehydrogenases, 3-hydroxyacyl; beta hydroxyacyl dehydrogenases; 3 hydroxyacyl CoA dehydrogenases;

CISMeF synonym : (S)-3-Hydroxyacyl-CoA:NAD oxidoreductase; beta hydroxyacyl CoA dehydrogenase; beta-Hydroxyacyl CoA dehydrogenase; CoA dehydrogenase, beta-Hydroxyacyl; dehydrogenase, beta-Hydroxyacyl CoA;

Registry Number MeSH : EC 1.1.1.35; EC 1.1.1.-;

Is substance : O;

Details

Origin ID

D015094;

UMLS CUI

C0000404;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- LCHAD deficiency [MedDRA LLT]
- Long-chain-3-hydroxyacyl-coenzyme A dehydrogenase (substance) [SNOMED CT concept]
- Peroxisomal Multifunctional Enzyme Type 2 [NCIt concept]
- hydroxysteroid 17-beta dehydrogenase 4 [ORDO Gene]
- hydroxysteroid 17-beta dehydrogenase 4 [HGNC gene]
Currated CISMeF NLP mapping
- 3-hydroxyacyl-coa dehydrogenase [SNOMED Notion]
- 3-hydroxyacyl-coenzyme A dehydrogenase (substance) [SNOMED CT concept]
Manual NTBT mappings (CISMeF)
- Disorder of fatty acid oxidation and ketone body metabolism [ORDO Disease]
- Fatty acid oxidation and ketogenesis disorder with hypertrophic cardiomyopathy [ORDO Disease]
- Metabolic disease with pigmentary retinitis [ORDO Disease]
- Rare hereditary metabolic disease with peripheral neuropathy [ORDO Disease]
- Syndrome with hypoparathyroidism [ORDO Disease]
Record concept(s)
- 3-Hydroxyacyl CoA dehydrogenases [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-methyl-3-hydroxybutyryl-coenzyme A dehydrogenase [MeSH Supplementary Concept]
- 3-hydroxyacyl-coa dehydrogenase deficiency [MeSH Supplementary Concept]
- 3-hydroxybutyryl-CoA dehydrogenase [MeSH Supplementary Concept]
- 3-oxobutyryl-CoA reductase [MeSH Supplementary Concept]
- FOX2 protein, S cerevisiae [MeSH Supplementary Concept]
- HSD17B10 protein, human [MeSH Supplementary Concept]
- Hsd17b10 protein, mouse [MeSH Supplementary Concept]
- MFE-2 protein, C elegans [MeSH Supplementary Concept]
- YBR159W protein, S cerevisiae [MeSH Supplementary Concept]
- fatty acid oxidation complex [MeSH Supplementary Concept]
- hydroxyacyl-Coenzyme A dehydrogenase, type II, rat [MeSH Supplementary Concept]
- palmitoyl-CoA dependent dehydrogenase [MeSH Supplementary Concept]
- scu protein, drosophila [MeSH Supplementary Concept]
- trifunctional protein deficiency with myopathy and neuropathy [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency [ORDO Disease]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 3-Hydroxyacyl-CoA Dehydrogenase [NCIt concept]
Validated automatic mappings to BTNT
- 3-Hydroxyacyl-CoA Dehydrogenase [NCIt concept]

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