Preferred Label : von willebrand factor;
MeSH definition : A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes,
that is part of the factor VIII/von Willebrand factor complex. The von Willebrand
factor has receptors for collagen, platelets, and ristocetin activity as well as the
immunologically distinct antigenic determinants. It functions in adhesion of platelets
to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND
DISEASES is due to the deficiency of this factor.;
MeSH synonym : factor viii related antigen; von willebrand protein; factor viiir rco; factor viiir-rco; ristocetin willebrand factor; factor viiir-ag; factor viiir ag; ristocetin-willebrand factor; factor viii-related antigen; ristocetin cofactor;
CISMeF synonym : von willebrand factor type iib; antigen, factor viii-related; protein, von willebrand; vwf ag; ag, vwf; cofactor, ristocetin; f viii vwf; f viii-vwf; von Willebrand; Willebrand;
MeSH Hyperonym : plasma factor VIII complex;
MeSH annotation : / defic VON WILLEBRAND DISEASE or specific type of Von Willebrand Disease;
Wikipedia link : https://en.wikipedia.org/wiki/Von willebrand factor;
Is substance : O;
Origin ID : D014841;
UMLS CUI : C0042971;
- ATC code(s)
- Allowable qualifiers
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- Indexing information
- saratin [MeSH Supplementary Concept]
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- AR545C [MeSH Supplementary Concept]
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes,
that is part of the factor VIII/von Willebrand factor complex. The von Willebrand
factor has receptors for collagen, platelets, and ristocetin activity as well as the
immunologically distinct antigenic determinants. It functions in adhesion of platelets
to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND
DISEASES is due to the deficiency of this factor.
https://ansm.sante.fr/informations-de-securite/veyvondiv-vonicog-alfa-facteur-von-willebrand-humain-recombinant-poudre-et-solvant-pour-solution-injectable-mises-en-garde-sur-la-lecture-du-dosage-du-produit-et-sur-le-calcul-du-nombre-de-flacons-necessaires-vmedicament-sous-surveillance-ren
2023
false
false
false
France
French
product surveillance, postmarketing
drug information
Vonicog Alfa
recombinant proteins
von willebrand factor
injections, intravenous
hemorrhage
hemorrhage
adult
von willebrand diseases
blood loss, surgical
blood loss, surgical
---
https://www.inesss.qc.ca/publications/repertoire-des-publications/publication/vonvendimc-vonicog-alfa-facteur-de-von-willebrand-recombinant-maladie-de-von-willebrand-mise-a-jour-de-la-liste-des-produits-du-systeme-du-sang-du-quebec-janvier-2020.html
2020
false
false
false
Canada
technical report
Willebrand disease
von willebrand disease, platelet type
blood
quebec
waiting lists
von willebrand diseases
von willebrand factor
von willebrand disease, nos
von willebrand factor
von willebrand disease, platelet type
Diseases
---
https://www.has-sante.fr/portail/jcms/c_2891542/fr/veyvondi
2019
false
false
false
France
French
evaluation of the transparency committee
recombinant proteins
treatment outcome
Vonicog Alfa
von willebrand factor
adult
hemorrhage
hemorrhage
postoperative complications
postoperative complications
von willebrand diseases
blood loss, surgical
blood loss, surgical
injections, intravenous
von Willebrand factor
---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00434
2019
false
false
false
Canada
French
drug information
von willebrand factor
von willebrand factor
recombinant proteins
drug approval
canada
injections, intravenous
hemorrhage
hemorrhage
von willebrand diseases
adult
treatment outcome
blood loss, surgical
blood loss, surgical
von Willebrand factor
---
https://www.ema.europa.eu/medicines/human/EPAR/Veyvondi
2018
false
false
false
United Kingdom
French
English
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
treatment outcome
von Willebrand factor
product surveillance, postmarketing
hemorrhage
blood loss, surgical
blood loss, surgical
von willebrand diseases
von willebrand factor
injections, intravenous
adult
pregnancy
breast feeding
recombinant proteins
drug evaluation, preclinical
---
https://anpgm.fr/media/documents/anpgm_135-deficits_constitutionnels_rares_en_facteurs_de_coagulation.pdf
2018
France
guideline
hemophilia b, nos
coagulation factor, nos
Hemophilia B
blood coagulation disorder, nos
genes
coagulants
hemophilia B
von willebrand diseases
von willebrand factor
Rare disease
Coagulation factors
rare diseases
Diseases
coagulants
---
http://www.theses.fr/2018LIL2S039
2018
France
dissertations, academic
equipment and supplies
postman
mechanics
von willebrand factor
Applications
device, nos
hemodynamics
devices
Applications
attention
Applications
---
https://www.has-sante.fr/portail/jcms/c_2863574/fr/eqwilate
https://www.has-sante.fr/portail/jcms/c_2863574/fr/eqwilate-facteur-von-willebrand-facteur-viii-de-coagulation-humain
2018
false
false
false
false
France
French
evaluation of the transparency committee
drug combinations
treatment outcome
von willebrand factor
F8 protein, human
hemophilia A
von willebrand diseases
hemorrhage
hemorrhage
blood loss, surgical
blood loss, surgical
guidelines for drug use
von willebrand factor and coagulation factor VIII in combination
factor VIII
---
http://www.has-sante.fr/portail/jcms/c_2642074/fr/voncento
http://www.has-sante.fr/portail/jcms/c_2642074/fr/voncento-facteur-viii-de-coagulation-humain-facteur-von-willebrand
2016
false
false
false
false
France
French
evaluation of the transparency committee
treatment outcome
drug combinations
von willebrand factor
factor VIII
hemorrhage
hemorrhage
von willebrand diseases
postoperative hemorrhage
postoperative hemorrhage
blood loss, surgical
blood loss, surgical
hemophilia A
injections, intravenous
infusions, intravenous
von willebrand factor and coagulation factor VIII in combination
child
guidelines for drug use
---
http://www.has-sante.fr/portail/jcms/c_1747223/fr/voncento-facteur-viii-de-coagulation-humain-facteur-von-willebrand-facteurs-de-coagulation
2014
false
false
false
France
French
guidelines for drug use
evaluation of the transparency committee
treatment outcome
drug combinations
von willebrand factor
factor VIII
hemorrhage
hemorrhage
von willebrand diseases
postoperative hemorrhage
postoperative hemorrhage
blood loss, surgical
blood loss, surgical
hemophilia A
injections, intravenous
infusions, intravenous
von willebrand factor and coagulation factor VIII in combination
---
http://www.has-sante.fr/portail/jcms/c_1766748/fr/wilfactin
http://www.has-sante.fr/portail/jcms/c_399932/fr/wilfactin-100-ui/ml-poudre-et-solvant-pour-solution-injectable
2014
false
France
French
hemorrhage
hemorrhage
surgical procedures, operative
evaluation of the transparency committee
von willebrand factor
von Willebrand factor
injections, intravenous
treatment outcome
von willebrand diseases
---
https://www.ema.europa.eu/medicines/human/EPAR/Voncento
2013
false
United Kingdom
French
English
factor VIII
F8 protein, human
von willebrand factor
drug combinations
von willebrand factor
F8 protein, human
factor VIII
drug approval
treatment outcome
europe
hemophilia A
blood loss, surgical
hemorrhage
hemorrhage
von willebrand diseases
postoperative hemorrhage
postoperative hemorrhage
injections, intravenous
infusions, intravenous
von willebrand factor and coagulation factor VIII in combination
product surveillance, postmarketing
pregnancy
summary of product characteristics
package leaflet
drug evaluation
syndication feed
---