trimethoprim - CISMeF

Preferred Label : trimethoprim;

MeSH definition : A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.;

MeSH hyponym : proloprim; trimpex;

MeSH CAS label : 2,4-Pyrimidinediamine, 5-((3,4,5-trimethoxyphenyl)methyl)-;

MeSH Related Number : 738-70-5 (Trimethoprim);

Registry Number MeSH : 738-70-5;

MeSH annotation : consider TRIMETHOPRIM RESISTANCE for nonsusceptibility of bacteria;

Wikipedia link : https://en.wikipedia.org/wiki/Trimethoprim;

Codes EINECS : 212-006-2;

Is substance : O;

UNII : AN164J8Y0X;

InChIKey : IEDVJHCEMCRBQM-UHFFFAOYSA-N;

Details

Origin ID

D014295;

UMLS CUI

C0041041;

ATC code(s)
- combinations of sulfonamides and trimethoprim, incl. derivatives [ATC Code]
- isoniazid, sulfamethoxazole and trimethoprim [ATC Code]
- sulfadimidine and trimethoprim [ATC Code]
- sulfamerazine and trimethoprim [ATC Code]
- sulfametrole and trimethoprim [ATC Code]
- sulfamoxole and trimethoprim [ATC Code]
- sulfonamides and trimethoprim [ATC Code]
- trimethoprim [ATC Code]
- trimethoprim and derivatives [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Trimethoprim poisoning (disorder) [SNOMED CT concept]
- trimethoprim [Substance BNPC]
Pharmacological action(s)
- Cytochrome P-450 CYP2C8 Inhibitors [MeSH Descriptor]
- anti-dyskinesia agents [MeSH Descriptor]
- anti-infective agents, urinary [MeSH Descriptor]
- antimalarials [MeSH Descriptor]
- folic acid antagonists [MeSH Descriptor]
Record concept(s)
- proloprim [MeSH concept]
- trimethoprim [MeSH concept]
- trimpex [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2,4-diamino-5-((3,5-dimethoxy-4-(4-bromoacetamidophenoxy)benzyl)pyrimidine) [MeSH Supplementary Concept]
- 2,4-diamino-5-(2-methoxy-5-(4-carboxybutyloxy)benzyl)pyrimidine [MeSH Supplementary Concept]
- 2,4-diamino-5-(3,4-dimethoxy-5-(5-carboxy-1-pentynyl))benzylpyrimidine [MeSH Supplementary Concept]
- TMP-AcBOPDIPY probe [MeSH Supplementary Concept]
- aditoprim [MeSH Supplementary Concept]
- brodimoprim [MeSH Supplementary Concept]
- cotrifazid [MeSH Supplementary Concept]
- enrofloxacin-trimethoprim combination [MeSH Supplementary Concept]
- epiroprim [MeSH Supplementary Concept]
- kelfiprim [MeSH Supplementary Concept]
- lidaprim [MeSH Supplementary Concept]
- metioprim [MeSH Supplementary Concept]
- polytrim eyedrops [MeSH Supplementary Concept]
- potrox [MeSH Supplementary Concept]
- rifaprim [MeSH Supplementary Concept]
- sulfadiazine, trimethoprim drug combination [MeSH Supplementary Concept]
- sulfamoxole, trimethoprim drug combination [MeSH Supplementary Concept]
- sulfaton [MeSH Supplementary Concept]
- superseptyl (sulfamethazine), trimethoprim drug combination [MeSH Supplementary Concept]
- trimerazine [MeSH Supplementary Concept]
- trimethoprim picolinate [MeSH Supplementary Concept]
- trimethoprim sulfamethizole [MeSH Supplementary Concept]
- trimethoprim, sulfadoxine drug combination [MeSH Supplementary Concept]
See also
- trimethoprim resistance [MeSH Descriptor]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing trimethoprim (medicinal product) [SNOMED CT concept]
- Trimethoprim [ICD-11 Extension code]
- Trimethoprim [NCIt concept]
- Trimethoprim [LOINC component]
- Trimethoprim (substance) [SNOMED CT concept]
- trimethoprim [ATC Code]
- trimethoprim [Substance BNPC]
- trimethoprim [SNOMED Notion]
Validated automatic mappings to BTNT
- trimethoprim [ATC Code]

Keyword's position in hierarchy(ies) :

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