Trimethoprim - CISMeF

Preferred Label : Trimethoprim;

NCIt synonyms : 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;

NCIt related terms : Proloprim; Trimpex;

NCIt definition : A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04);

UNII : AN164J8Y0X;

InChIKey : IEDVJHCEMCRBQM-UHFFFAOYSA-N;

CAS number : 738-70-5;

Drug name : Trimpex; Proloprim;

Chemical formula : C14H18N4O3;

NSC code : 106568;

ChEBI ID : CHEBI:45924;

Codes from synonyms : NSC0106568;

Details

Origin ID

C908;

UMLS CUI

C0041041;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing trimethoprim (medicinal product) [SNOMED CT concept]
- Trimethoprim [ICD-11 Extension code]
- Trimethoprim [LOINC component]
- Trimethoprim (substance) [SNOMED CT concept]
- trimethoprim [ATC Code]
- trimethoprim [Substance BNPC]
- trimethoprim [MeSH Descriptor]
- trimethoprim [MeSH concept]
- trimethoprim [SNOMED Notion]
Validated automatic mappings to BTNT
- trimethoprim [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Trimethoprim Hydrochloride [NCIt concept]
- Trimethoprim Sulfate [NCIt concept]
is_free_acid_or_base_form_of
- Trimethoprim Hydrochloride [NCIt concept]
- Trimethoprim Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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