Preferred Label : Trimethoprim;

NCIt synonyms : 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;

NCIt related terms : Proloprim; Trimpex;

NCIt definition : A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04);

UNII : AN164J8Y0X;

InChIKey : IEDVJHCEMCRBQM-UHFFFAOYSA-N;

CAS number : 738-70-5;

Drug name : Trimpex; Proloprim;

Chemical formula : C14H18N4O3;

NSC code : 106568;

ChEBI ID : CHEBI:45924;

Codes from synonyms : NSC0106568;

Details


Main resources

You can consult :


https://medqual.fr/images/2024-COTRIMOXAZOLE.pdf
2024
France
patient education handout
drug information
trimethoprim
sulfamethoxazole
Trimethoprim
co-trimazole
Sulfamethoxazole

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28/05/2025


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