Preferred Label : hydroxyzine;
MeSH definition : A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria,
dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE,
it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety
and tension, and as a sedative.;
MeSH synonym : 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol;
CISMeF synonym : 10246-75-0 (Hydroxyzine pamoate);
MeSH hyponym : orgatrax; durrax; atarax; vistaril; Hydroxyzine Hydrochloride; Hydroxyzine Dihydrochloride; Hydroxyzine Pamoate; Pamoate, Hydroxyzine;
MeSH CAS label : ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-;
MeSH Related Number : hydroxyzine dihydrochloride; hydroxyzine pamoate; 10246-75-0 (pamoate); 2192-20-3 (di-HCl); 68-88-2 (Hydroxyzine); hydroxyzine hydrochloride; 76755771U3; M20215MUFR;
Registry Number MeSH : 68-88-2;
Related CAS MeSH : 2192-20-3 (Hydroxyzine dihydrochloride); M20215MUFR (Hydroxyzine pamoate); 76755771U3 (Hydroxyzine hydrochloride);
Wikipedia link : https://en.wikipedia.org/wiki/Hydroxyzine;
Codes EINECS : 200-693-1;
Is substance : O;
UNII : 30S50YM8OG;
InChIKey : ZQDWXGKKHFNSQK-UHFFFAOYSA-N;
Origin ID : D006919;
UMLS CUI : C0020404;
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Currated CISMeF NLP mapping
Manual BTNT mappings - CISMeF
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- dormax [MeSH Supplementary Concept]
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria,
dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE,
it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety
and tension, and as a sedative.
https://www.has-sante.fr/jcms/p_3534473/fr/hydroxyzine-renaudin-hydroxyzine-premedication
2024
false
false
false
France
insurance, health, reimbursement
treatment outcome
hydroxyzine
injections, intravenous
injections, intramuscular
evaluation of the transparency committee
preanesthetic medication
hydroxyzine
---
https://www.has-sante.fr/jcms/p_3280950/fr/hydroxyzine-bluefish-hydroxyzine-chlorhydrate-d
2021
false
false
false
France
administration, oral
treatment outcome
insurance, health, reimbursement
histamine h1 antagonists
antipruritics
Product containing precisely hydroxyzine hydrochloride 25 milligram/1 each conventional
release oral tablet (clinical drug)
Product containing precisely hydroxyzine hydrochloride 10 milligram/1 each conventional
release oral tablet (clinical drug)
adult
anxiety
anxiety disorders
pruritus
urticaria
hydroxyzine
evaluation of the transparency committee
Hydroxyzine Hydrochloride
hydroxyzine
---
https://www.has-sante.fr/portail/jcms/c_2775790/fr/atarax
https://www.has-sante.fr/portail/jcms/c_486519/fr/atarax
2017
false
false
France
French
sleep initiation and maintenance disorders
hydroxyzine
anti-anxiety agents
administration, oral
insurance, health, reimbursement
histamine h1 antagonists
antipruritics
preanesthetic medication
urticaria
anxiety disorders
hydroxyzine
evaluation of the transparency committee
---
ATARAX (hydroxyzine) - Risk of QT Prolongation and Torsade de Pointes
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2016/58758a-fra.php
2016
false
false
false
Canada
French
English
pharmacovigilance note
administration, oral
hydroxyzine
hydroxyzine
risk
hydroxyzine
adult
aged
child
adolescent
hydroxyzine
Product containing precisely hydroxyzine hydrochloride 10 milligram/1 each conventional
release oral tablet (clinical drug)
Product containing precisely hydroxyzine hydrochloride 50 milligram/1 each conventional
release oral tablet (clinical drug)
Product containing precisely hydroxyzine hydrochloride 25 milligram/1 each conventional
release oral tablet (clinical drug)
Hydroxyzine hydrochloride 10mg/5mL syrup (product)
Product containing hydroxyzine in parenteral dose form (medicinal product form)
injections
long qt syndrome
torsades de pointes
histamine h1 antagonists
histamine h1 antagonists
histamine h1 antagonists
Contraindications, Procedure
Contraindications, Drug
---
Summary Safety Review - Hydroxyzine (ATARAX and generics) - Assessing the Potential
Risk of Abnormal Heart Rhythm
https://www.hc-sc.gc.ca/dhp-mps/medeff/reviews-examens/atarax-fra.php
2016
false
false
false
Canada
French
English
drug evaluation
risk assessment
canada
hydroxyzine
hydroxyzine
histamine h1 antagonists
drugs, generic
risk factors
arrhythmias, cardiac
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63999867
2012
France
summary of product characteristics
package leaflet
hydroxyzine
injections
---
http://www.cochrane.org/fr/CD006815
2010
United Kingdom
France
French
meta-analysis
hydroxyzine
anxiety disorders
treatment outcome
french abstract
Generalized anxiety disorder
---
http://www.lecrat.eu/?s=Hydroxyzine
2009
France
French
pregnancy
hydroxyzine
histamine h1 antagonists
infant, newborn
breast feeding
hydroxyzine
drug information
---
http://www.meddispar.fr/medicaments/3008143
2008
France
French
administration, oral
hydroxyzine
drug prescriptions
pharmaceutical solutions
legislation, drug
hydroxyzine
drug information
---
http://www.meddispar.fr/medicaments/3008137
2008
France
French
drug prescriptions
hydroxyzine
administration, oral
tablets
legislation, drug
hydroxyzine
drug information
---
http://www.has-sante.fr/portail/display.jsp?id=c_538431
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-4129_atarax_.pdf
http://www.has-sante.fr/portail/upload/docs/application/pdf/2009-06/ct_4129_atarax_ang.pdf
2007
France
English
French
evaluation of the transparency committee
pharmaceutical solutions
hydroxyzine
tablets
hydroxyzine
anti-anxiety agents
insurance, health, reimbursement
child
sleep initiation and maintenance disorders
administration, oral
histamine h1 antagonists
treatment outcome
---