Preferred Label : Hydroxyzine Pamoate;
NCIt synonyms : Atarax P; Paxistil; Masmoran; 2-(2-(4-(p-Chloro-alpha-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol 4,4'-methylenebis(3-hydroxy-2-naphthoate)
(1:1); Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, compound with
4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic Acid)(1:1);
NCIt definition : The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor
antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety
properties. Hydroxyzine pamoate blocks the H1 histamine receptor and prevents the
symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle,
and gastrointestinal smooth muscle, including vasodilatation, increased capillary
permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth
muscle. In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts
on the histamine H1-receptors in the central nervous system. (NCI05);
UNII : M20215MUFR;
InChIKey : ASDOKGIIKXGMNB-UHFFFAOYSA-N;
CAS number : 10246-75-0;
Drug name : Vistaril;
Chemical formula : C23H16O6.C21H27ClN2O2;
ChEBI ID : CHEBI:31680;
Origin ID : C47560;
UMLS CUI : C0700539;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
