Hydroxyzine - CISMeF

Preferred Label : Hydroxyzine;

NCIt definition : A piperazine derivative with antihistamine, antiemetic, and anxiolytic properties. Hydroxyzine's antihistaminic effect is due to its metabolite, cetirizine, a potent H1 receptor antagonist and selective inhibitor of peripheral H1 receptors. This agent competes with histamine for binding at H1-receptor sites on the effector cell surface. The sedative properties of hydroxyzine occur as a result of suppression of certain subcortical regions of the brain. Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic.;

UNII : 30S50YM8OG;

InChIKey : ZQDWXGKKHFNSQK-UHFFFAOYSA-N;

CAS number : 68-88-2;

Chemical formula : C21H27ClN2O2;

NSC code : 169188;

ChEBI ID : CHEBI:5818;

Codes from synonyms : 46632;

Details

Origin ID

C29103;

UMLS CUI

C0020404;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Hydroxyzine [ICD-11 Extension code]
- Hydroxyzine (substance) [SNOMED CT concept]
- Product containing hydroxyzine (medicinal product) [SNOMED CT concept]
- hydrOXYzine [LOINC component]
- hydroxyzine [ATC Code]
- hydroxyzine [Substance BNPC]
- hydroxyzine [SNOMED Notion]
- hydroxyzine [MeSH Descriptor]
- hydroxyzine [MeSH concept]
Validated automatic mappings to BTNT
- hydroxyzine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Hydroxyzine Hydrochloride [NCIt concept]
- Hydroxyzine Pamoate [NCIt concept]
is_free_acid_or_base_form_of
- Hydroxyzine Hydrochloride [NCIt concept]
- Hydroxyzine Pamoate [NCIt concept]

Keyword's position in hierarchy(ies) :

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