dapsone - CISMeF

Preferred Label : dapsone;

MeSH definition : A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8);

MeSH synonym : sulfonyldianiline; sulfone, 4,4'-diaminophenyl; dadps; diaminodiphenylsulfone; diaphenylsulfone; 4,4'-diaminophenyl sulfone; 4,4' diaminophenyl sulfone;

CISMeF synonym : Mex-America brand of dapsone; fatol brand of dapsone; orsade brand of dapsone;

MeSH hyponym : sulfona; disulone; Dapsoderm-X; avlosulfone; Dapson-Fatol;

MeSH Related Number : 80-08-0 (Dapsone);

Registry Number MeSH : 80-08-0;

Wikipedia link : https://en.wikipedia.org/wiki/Dapsone;

Codes EINECS : 201-248-4;

Is substance : O;

UNII : 8W5C518302;

InChIKey : MQJKPEGWNLWLTK-UHFFFAOYSA-N;

Details

Origin ID

D003622;

UMLS CUI

C0010980;

ATC code(s)
- dapsone [ATC Code]
- dapsone [ATC Code]
- dapsone and rifampicin [ATC Code]
- dapsone, rifampicin and clofazimine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 4,4-Oxydianiline [NCIt concept]
- Deoxy adenosine diphosphate (substance) [SNOMED CT concept]
CISMeF manual mappings
- dapsone [Substance BNPC]
Currated CISMeF NLP mapping
- Dapsone [ICD-11 Extension code]
- Dapsone [LOINC component]
- Dapsone [ICHI extension code]
- Dapsone [SMS substance]
- Dapsone [NCIt concept]
- Dapsone (substance) [SNOMED CT concept]
- Diaphenylsulfone [ICD-11 Extension code]
- Diaphenylsulfone [ICHI extension code]
- dapsone [SNOMED Notion]
Pharmacological action(s)
- antimalarials [MeSH Descriptor]
- folic acid antagonists [MeSH Descriptor]
- leprostatic agents [MeSH Descriptor]
Record concept(s)
- Dapsoderm-X [MeSH concept]
- Dapson-Fatol [MeSH concept]
- avlosulfone [MeSH concept]
- dapsone [MeSH concept]
- disulone [MeSH concept]
- sulfona [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4'-amino-4-n-propylamino-2-methyldiphenylsulfone [MeSH Supplementary Concept]
- 4,4'-dibutyrylaminodiphenyl sulfone [MeSH Supplementary Concept]
- 4,4'-disuccinoylaminodiphenyl sulfone [MeSH Supplementary Concept]
- 4-amino-4'-hydroxylaminodiphenylsulfone [MeSH Supplementary Concept]
- 4-amino-p'-ureidodiphenylsulfone [MeSH Supplementary Concept]
- 4-nitro-4'-aminodiphenyl sulfone [MeSH Supplementary Concept]
- SDDS [MeSH Supplementary Concept]
- chloroguanil, dapsone drug combination [MeSH Supplementary Concept]
- dapsone, methyluracil drug combination [MeSH Supplementary Concept]
- diformyl dapsone [MeSH Supplementary Concept]
- glucosulfone [MeSH Supplementary Concept]
- isoprodian [MeSH Supplementary Concept]
- maloprim [MeSH Supplementary Concept]
- monoacetyldapsone [MeSH Supplementary Concept]
- monoacetyldapsone hydroxylamine [MeSH Supplementary Concept]
- monolauryldapsone [MeSH Supplementary Concept]
- novolep [MeSH Supplementary Concept]
- sulfoxone [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing dapsone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dapsone [ICD-11 Extension code]
- Dapsone [LOINC part]
- Dapsone [NCIt concept]
- Dapsone [LOINC component]
- Dapsone (substance) [SNOMED CT concept]
- Product containing dapsone (medicinal product) [SNOMED CT concept]
- dapsone [ATC Code]
- dapsone [ATC Code]
- dapsone [Substance BNPC]
- dapsone [SNOMED Notion]
Validated automatic mappings to BTNT
- dapsone [ATC Code]
- dapsone [ATC Code]

Keyword's position in hierarchy(ies) :

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