Preferred Label : colchicine;

MeSH definition : A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).;

MeSH hyponym : colchicine, (R)-Isomer; colchicine, ( -)-Isomer;

MeSH CAS label : acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-;

MeSH Related Number : colchicine, (R)-Isomer; colchicine, ( -)-Isomer; 54192-66-4 (( -)-isomer); 64-86-8 (Colchicine); 75520-89-7 ((R)-isomer);

Registry Number MeSH : 64-86-8;

Related CAS MeSH : 75520-89-7 (Colchicine, (R)-Isomer); 54192-66-4 (Colchicine, ( -)-Isomer);

Wikipedia link : https://en.wikipedia.org/wiki/Colchicine;

Codes EINECS : 200-598-5;

Is substance : O;

UNII : SML2Y3J35T;

InChIKey : IAKHMKGGTNLKSZ-INIZCTEOSA-N;

Details


Main resources

You can consult :

A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).

https://www.rheuma-net.ch/fr/doc/colchicine/viewdocument/491
2024
Switzerland
guideline
Background Treatment
colchicine
colchicine
Colchicine

---
https://www.cbip.be/fr/articles/4315?folia=4305
2024
false
false
false
Belgium
French
Dutch
journal article
colchicine
risk
risk management
Narrow Therapeutic Index
narrow therapeutic range drugs

---
https://ansm.sante.fr/informations-de-securite/prise-en-charge-par-colchicine-de-la-goutte-une-nouvelle-posologie-plus-faible-et-un-message-dalerte-sur-les-boites-pour-reduire-le-risque-de-surdosage
2023
false
false
false
France
French
risk management
colchicine
colchicine
gout
guidelines for drug use
gout suppressants
gout suppressants
colchicine

---
https://ansm.sante.fr/informations-de-securite/intoxications-graves-a-la-colchicine-colchicine-opocalcium-1-mg-et-colchimax-rappel-des-regles-de-bon-usage
2022
false
false
false
France
French
colchicine
administration, oral
pharmacovigilance note
guidelines for drug use
colchicine
gout suppressants
drug combinations
aged

---
https://www.cochrane.org/fr/CD015045/HAEMATOL_la-colchicine-est-elle-un-traitement-efficace-chez-les-personnes-atteintes-de-la-covid-19
2021
false
false
false
United Kingdom
COVID-19
treatment outcome
review of literature
french abstract
colchicine

---
https://www.usherbrooke.ca/baladocritique/archives/episode-42-etude-colcorona/
2021
false
false
false
Canada
sound
COVID-19
pneumonia, viral
coronavirus infections
pandemics
disease
efficiency
persons
colchicine
episode of
colchicine
data collection

---
https://www.inesss.qc.ca/covid-19/traitements-specifiques-a-la-covid-19/colchicine.html
2021
false
false
false
Canada
coronavirus infections
pneumonia, viral
scientific and technical information
treatment outcome
inflammation
Respiratory Distress Syndrome
drug information
colchicine
pneumonia, viral
coronavirus infections
pandemics
pandemics
COVID-19
COVID-19

---
http://www.cochrane.org/fr/CD006190
2021
false
true
false
United Kingdom
France
treatment outcome
meta-analysis
french abstract
gout
colchicine

---
https://www.cochrane.org/fr/CD011047/VASC_effets-et-innocuite-de-lutilisation-long-terme-de-la-colchicine-sur-les-maladies-cardiaques
2020
false
false
false
France
United Kingdom
colchicine
treatment outcome
review of literature
french abstract
heart diseases
colchicine
time

---
https://www.usherbrooke.ca/baladocritique/archives/episode-36-etude-lodoco2/
2020
Canada
sound
coronary disease
colchicine
Diseases
data collection
coronary artery disease
disease, nos
colchicine
persons
Disease
coronary disease

---
https://www.usherbrooke.ca/baladocritique/archives/episode-29-etude-colcot/
2019
false
false
false
Canada
colchicine
treatment outcome
myocardial infarction
colchicine
sound

---
https://www.has-sante.fr/portail/jcms/c_2847892/fr/colchicine-opocalcium
2018
false
France
French
Acute idiopathic pericarditis (disorder)
treatment outcome
pericarditis
drug therapy, combination
anti-inflammatory agents
colchicine
administration, oral
insurance, health, reimbursement
evaluation of the transparency committee

---
https://www.has-sante.fr/portail/jcms/c_2847889/fr/colchimax
2018
false
France
French
Acute idiopathic pericarditis (disorder)
treatment outcome
pericarditis
drug therapy, combination
anti-inflammatory agents
morpholines
drug combinations
opium
colchicine
tiemonium methylsulfate
administration, oral
insurance, health, reimbursement
evaluation of the transparency committee

---
https://www.inspq.qc.ca/publications/2224
2017
false
true
false
France
French
technical report
gout suppressants
tubulin modulators
colchicine
poisoning by colchicine

---
https://www.has-sante.fr/portail/jcms/c_2800416/fr/thiocolchicoside-biogaran
2017
false
false
false
France
French
evaluation of the transparency committee
thiocolchicoside
colchicine

---
https://www.has-sante.fr/portail/jcms/c_2800431/fr/thiocolchicoside-almus
2017
false
false
false
France
French
evaluation of the transparency committee
thiocolchicoside
colchicine

---
http://www.sudoc.fr/203043502
2017
false
false
false
France
French
dissertations, academic
drug, nos
professional practice
prescription, nos
occupational
risk assessment
drug evaluation
colchicine
colchicine

---
http://www.prescrire.org/Fr/3/31/53004/0/NewsDetails.aspx
2017
false
false
false
France
French
french abstract
attention, nos
poisoning by colchicine
colchicine
drug addicts
poisoning
attention
drug users

---
https://nantilus.univ-nantes.fr/vufind/Record/PPN193890380
2016
false
false
false
France
French
dissertations, academic
colchicine
gout

---
https://centres-antipoison.net/wp-content/uploads/2017/08/CCTV_Colchicine_rapport_VF_octobre_2014.pdf
2016
false
false
false
France
French
colchicine
administration, oral
Accidental colchicine poisoning (disorder)
Colchicine poisoning of undetermined intent (disorder)
Intentional colchicine poisoning (disorder)
france
poisoning
medication errors
poisoning
colchicine
colchicine
technical report

---
https://www.inspq.qc.ca/toxicologie-clinique/vers-l-emergence-d-intoxications-aigues-par-la-colchicine
2015
false
true
false
Canada
French
journal article
colchicine
colchicine
colchicine
colchicine
drug monitoring
antirheumatic agents

---
http://www.lecrat.eu/?s=Colchicine+-+exposition+paternelle
France
drug information
colchicine
teratogens
pregnancy, nos
pregnancy, high-risk
paternal exposure

---
http://www.pharmactuel.com/index.php/pharmactuel/article/view/923
2013
false
false
false
Canada
French
anti-inflammatory agents
tubulin modulators
pericarditis
atrial fibrillation
coronary arteriosclerosis
coronary artery disease
colchicine
drug interactions
colchicine
colchicine
cardiovascular diseases
journal article
colchicine

---
https://www.minerva-ebp.be/fr/article/62
2013
false
false
minerva-ebm.be
Belgium
French
colchicine
secondary prevention
treatment outcome
critical appraisal or critical reading
acute coronary syndrome
coronary disease
plaque, atherosclerotic

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68066715
2012
France
summary of product characteristics
package leaflet
colchicine
tablets

---
https://www.minerva-ebp.be/fr/article/247
2011
false
true
false
false
minerva-ebm.be
Belgium
arthritis, gouty
colchicine
colchicine
colchicine
critical appraisal or critical reading
colchicine

---
https://medicalforum.ch/fr/detail/doi/fms.2011.07689/
2011
false
true
false
Switzerland
colchicine
colchicine
colchicine
signs and symptoms
journal article

---
http://www.revmed.ch/RMS/2010/RMS-N-267/Une-prise-en-charge-sur-mesure-de-la-pericardite
2010
false
true
false
Switzerland
colchicine
colchicine
colchicine
colchicine
pericarditis
pericarditis
journal article
pericarditis

---
http://www.cochrane.org/fr/CD003273
2010
false
true
false
France
United Kingdom
treatment outcome
review of literature
french abstract
colchicine
asthma

---
http://www.lecrat.eu/?s=Colchicine
2010
France
French
pregnancy
colchicine
tubulin modulators
gout suppressants
colchicine
drug information

---
http://www.has-sante.fr/portail/display.jsp?id=c_400857
http://www.has-sante.fr/portail/jcms/c_1013248/colchimax
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-01/colchimax_-_ct9493.pdf
2010
France
French
tablets
morpholines
drug combinations
gout suppressants
opium
colchicine
tiemonium methylsulfate
preparations with no effect on uric acid metabolism
administration, oral
insurance, health, reimbursement
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-01/colchicine_-_ct-8592.pdf
http://www.has-sante.fr/portail/jcms/c_1016658/colchicine-opocalcium
2010
France
French
colchicine
administration, oral
colchicine
gout suppressants
insurance, health, reimbursement
treatment outcome
evaluation of the transparency committee

---
http://www.lecrat.eu/?s=Thiocolchicoside
2009
France
French
colchicine
pregnancy
breast feeding
neuromuscular agents
thiocolchicoside
thiocolchicoside
drug information

---
http://www.fondation-groupama.com/wp-content/uploads/2017/02/fievre_mediterraneenne_familiale.pdf
2009
false
true
false
France
French
popular works
scientific and technical information
familial mediterranean fever
child
adolescent
young adult
familial mediterranean fever
familial mediterranean fever
prevalence
familial mediterranean fever
familial mediterranean fever
signs and symptoms
familial mediterranean fever
comorbidity
familial mediterranean fever
colchicine
pregnancy
breast feeding
biomedical research
Mainstreaming, Education
familial mediterranean fever

---
http://www.cbip.be/Folia/Index.cfm?FoliaWelk=F36F11F
2009
Belgium
Dutch
French
ATP Binding Cassette Transporter, Subfamily B, Member 1
drug interactions
cytochrome p-450 cyp3a
colchicine
journal article
pharmacovigilance note

---
https://centres-antipoison.net/wp-content/uploads/2017/08/rapport_CCTV_Colchicine_2008.pdf
2008
France
French
technical report
drug information
colchicine
data collection
Drug-Related side effects and adverse reactions
france
acute disease

---
https://rmlg.uliege.be/article/1513
2007
Belgium
French
corticosteroid therapy
pericarditis
recurrence
cardiovascular agents
colchicine
journal article

---
http://www.has-sante.fr/portail/display.jsp?id=c_400856
2006
France
evaluation of the transparency committee
colchicine
tablets

---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=31824
2006
France
French
gout suppressants
colchicine
colchicine
gout suppressants
Drug-Related side effects and adverse reactions
Drug-Related side effects and adverse reactions
signs and symptoms
Drug-Related side effects and adverse reactions
colchicine
gout suppressants
incidence
scientific and technical information

---
http://www.toxi.ch/upload/pdf/MB_Colchicum_F.pdf
2003
Switzerland
scientific and technical information
poisoning
confusion
drug addicts
colchicum
garlic
colchicine
ursidae
emergency medicine
plant leaves

---
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02/06/2024


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