Preferred Label : Biopterins;

MeSH definition : A natural product that has been considered as a growth factor for some insects.; Pterin derivatives based on 2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone. Biopterins are natural products that have been considered as growth factors for some insects. Biopterins are cofactors for the AROMATIC AMINO ACID hydroxylases and NITRIC OXIDE SYNTHASE. Deficiencies in BIOPTERINS metabolism (e.g., lowered TETRAHYDROBIOPTERIN) are associated with neurological deterioration (e.g., HYPERPHENYLALANINAEMIA).;

CISMeF synonym : [s-(r*,s*)]-2-amino-6-(1,2-dihydroxypropyl)-1h-pteridin-4-one; biopterin;

MeSH hyponym : 2-Amino-6-((1S,2R)-1,2-dihydroxypropyl)-4(1H)-pteridinone; 6-Biopterin; 6 Biopterin; L-Biopterin; L Biopterin; 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-, (S-(R*,S*))-; 2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone; L-erythro-Biopterin; L erythro Biopterin;

Related MeSH term : dictyopterin; orinapterin; 2-amino-6-((1R,2R)-1,2-dihydroxypropyl)-4(3H)-pteridinone; D-threo-Biopterin; D threo Biopterin; 2-Amino-6-(1,2-dihydroxypropyl)-4(8H)-pteridinone; L-threo-Biopterin; L threo Biopterin; 2-Amino-6-((1S,2S)-1,2-dihydroxypropyl)-4(1H)-pteridinone;

MeSH CAS label : 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-, (S-(R*,S*))-;

MeSH Related Number : 22150-76-1;

Registry Number MeSH : 22150-76-1;

MeSH annotation : /defic /physiol permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Biopterin;

Codes EINECS : 244-807-8;

Is substance : O;

Details


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A natural product that has been considered as a growth factor for some insects.
Pterin derivatives based on 2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone. Biopterins are natural products that have been considered as growth factors for some insects. Biopterins are cofactors for the AROMATIC AMINO ACID hydroxylases and NITRIC OXIDE SYNTHASE. Deficiencies in BIOPTERINS metabolism (e.g., lowered TETRAHYDROBIOPTERIN) are associated with neurological deterioration (e.g., HYPERPHENYLALANINAEMIA).

http://www.has-sante.fr/portail/jcms/c_2586909/fr/kuvan
2015
false
false
false
France
French
evaluation of the transparency committee
administration, oral
infant, newborn
child
infant
treatment outcome
sapropterin
sapropterin
phenylketonurias
hyperphenylalaninaemia
orphan drug production
sapropterin
Biopterins
Biopterins
Biopterins

---
http://www.cochrane.org/fr/CD008005
2015
false
France
United Kingdom
French
french abstract
meta-analysis
phenylketonurias
treatment outcome
Biopterins
sapropterin

---
https://www.ema.europa.eu/medicines/human/EPAR/Kuvan
2012
United Kingdom
French
English
syndication feed
tablets
administration, oral
drug approval
Biopterins
orphan drug production
treatment outcome
adult
adolescent
child
phenylketonurias
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
Biopterins
Biopterins
Biopterins
sapropterin
sapropterin
sapropterin
sapropterin
package leaflet
drug evaluation
summary of product characteristics

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Summary Basis of Decision (SBD) for KUVAN - Sapropterin dihydrochloride
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00083
2010
false
Canada
French
enzyme activators
phenylalanine hydroxylase
sapropterin
Biopterins
sapropterin
phenylketonurias
drug information

---
http://www.has-sante.fr/portail/jcms/c_757307/kuvan
http://www.has-sante.fr/portail/upload/docs/application/pdf/2009-03/kuvan_-_ct-6206.pdf
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-11/kuvan_ct_6206.pdf
2009
France
French
English
sapropterin
orphan drug production
sapropterin
Biopterins
administration, oral
phenylketonurias
adult
child
infant
treatment outcome
sapropterin
evaluation of the transparency committee
guidelines for drug use

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27/04/2025


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