phenylalanine hydroxylase

Preferred Label : phenylalanine hydroxylase;

MeSH definition : An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.;

MeSH synonym : hydroxylase, phenylalanine; phenylalanine 4-hydroxylase; 4-hydroxylase, phenylalanine; phenylalanine 4 hydroxylase; Phenylalanine 4-Monooxygenase; 4-monooxygenase, phenylalanine; phenylalanine 4 monooxygenase;

MeSH CAS label : L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating);

Registry Number MeSH : EC 1.14.16.1;

MeSH annotation : /defic: consider also PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL;

Is substance : O;

UNII : EC 1.14.16.1;

Details

Origin ID

D010651;

UMLS CUI

C0031456;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Classical phenylketonuria [ICD-11 Sub-sub category]
- Phenylalanine 4-monooxygenase (substance) [SNOMED CT concept]
- Phenylalanine hydroxylase [OMIM gene]
- Phenylalanine hydroxylase [LOINC component]
- phenylalanine 4-monooxygenase [SNOMED Notion]
- phenylalanine 4-monooxygenase activity [GO term]
- phenylalanine hydroxylase [HGNC gene]
- phenylalanine hydroxylase [ORDO Gene]
Indexing information
- 3,4-dihydroxystyrene [MeSH Supplementary Concept]
Record concept(s)
- phenylalanine hydroxylase [MeSH concept]
Related MeSH Supplementary Concept(s)
- hyperphenylalaninemia, Non-Pku mild [MeSH Supplementary Concept]
See also
- phenylketonuria, maternal [MeSH Descriptor]
- phenylketonurias [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Phenylalanine 4-monooxygenase (substance) [SNOMED CT concept]
- Phenylalanine hydroxylase [LOINC component]
- phenylalanine 4-monooxygenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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