Preferred Label : Doripenem;

MeSH definition : A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.;

MeSH hyponym : S-4661; S4661;

MeSH CAS label : 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((aminosulfonyl)amino)methyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-, (4R,5S,6S)-;

UNII : BHV525JOBH;

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A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.

http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66922406
2012
France
summary of product characteristics
package leaflet
powders
Doripenem

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https://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2012/14678a-fra.php
2012
false
Canada
English
French
antibiotic therapy
infusions, intravenous
anti-bacterial agents
doripenem
pneumonia, ventilator-associated
clinical trials, phase iii as topic
adult
cilastatin
imipenem
treatment outcome
drug combinations
imipenem and cilastatin
comparative study
pharmacovigilance note
Doripenem
Cilastatin, Imipenem Drug Combination

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61466272
2012
France
summary of product characteristics
package leaflet
powders
Doripenem

---
https://www.ema.europa.eu/medicines/human/EPAR/Doribax
2011
false
United Kingdom
English
French
syndication feed
antibiotic therapy
pregnancy
treatment outcome
drug approval
drug labeling
infusions, intravenous
adult
anti-bacterial agents
anti-bacterial agents
pneumonia, bacterial
urinary tract infections
cross infection
drug interactions
breast feeding
drug storage
drug compounding
abdominal cavity
Infections
doripenem
carbapenems
summary of product characteristics
package leaflet
drug evaluation
Doripenem
Doripenem

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28/05/2025


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