" /> Doripenem - CISMeF





Preferred Label : Doripenem;

NCIt definition : A broad-spectrum, carbapenem antibiotic with bactericidal and beta-lactamase resistant activities. Doripenem binds to penicillin binding proteins (PBPs) located on the bacterial cell wall, particularly PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition results in a weakening and eventually lysis of the bacterial cell wall. This agent is two- to 16-fold more potent than imipenem and comparable to ertapenem and meropenem.;

UNII : BHV525JOBH;

InChIKey : AVAACINZEOAHHE-VFZPANTDSA-N;

CAS number : 148016-81-3;

Drug name : FInibax; Doribax;

Molecule name : S-4661;

Chemical formula : C15H24N4O6S2;

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28/05/2025


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