Abciximab - CISMeF

Preferred Label : Abciximab;

MeSH definition : A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.;

MeSH synonym : c7E3 Fab; Chimeric 7E3 Fab; Fab, Chimeric 7E3;

MeSH Related Number : 143653-53-6 (Abciximab);

Wikipedia link : https://en.wikipedia.org/wiki/Abciximab;

UNII : X85G7936GV;

Détails

Origin ID

D000077284;

UMLS CUI

C0288672;

ATC code(s)
- abciximab [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Abciximab [NCIt concept]
- Abciximab [LOINC component]
- Abciximab [ICD-11 Extension code]
- Abciximab [SMS substance]
- Abciximab (substance) [SNOMED CT concept]
- abciximab [International Nonproprietary Name]
MeSH indexing information
- platelet glycoprotein GPIIb-IIIa complex [MeSH Descriptor]
Pharmacological action(s)
- anticoagulants [MeSH Descriptor]
- platelet aggregation inhibitors [MeSH Descriptor]
Record concept(s)
- CentoRx [MeSH concept]
- ReoPro [MeSH concept]
- abciximab [MeSH concept]
- clotinab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Abciximab [NCIt concept]
- Abciximab [LOINC component]
- Abciximab (substance) [SNOMED CT concept]
- Product containing abciximab (medicinal product) [SNOMED CT concept]
- abciximab [International Nonproprietary Name]
- abciximab [ATC Code]

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