Abciximab - CISMeF

Preferred Label : Abciximab;

NCIt synonyms : Chimeric 7E3 Fab; MoAb 7E3;

NCIt definition : A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation.;

UNII : X85G7936GV;

CAS number : 143653-53-6;

Drug name : ReoPro;

Codes from synonyms : 3;

Details

Origin ID

C76128;

UMLS CUI

C0288672;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Abciximab [MeSH Descriptor]
- Abciximab [LOINC component]
- Abciximab (substance) [SNOMED CT concept]
- Product containing abciximab (medicinal product) [SNOMED CT concept]
- abciximab [ATC Code]
- abciximab [International Nonproprietary Name]
- abciximab [MeSH concept]
Validated automatic mappings to BTNT
- abciximab [ATC Code]
chemical_or_drug_affects_gene_product
- Integrin Beta-3 [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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