immunoglobulin fab fragments

Preferred Label : immunoglobulin fab fragments;

MeSH definition : Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.;

MeSH synonym : fab fragment immunoglobulins; fab immunoglobulin fragments; fab fragments, immunoglobulin; fab fragments; immunoglobulin fab fragment; fab fragment, immunoglobulin; immunoglobulin fragments, fab; immunoglobulins, fab fragment; fragment immunoglobulins, fab; immunoglobulins, fab; Fab Fragment; Fragment, Fab; Ig Fab Fragments;

MeSH annotation : DF: IG FAB;

Is substance : O;

Details

Origin ID

D007140;

UMLS CUI

C0021031;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Fab Fragment [NCIt concept]
- Immunoglobulin, F(ab) fragment (substance) [SNOMED CT concept]
- immunoglobulin, f(ab) fragment [SNOMED Notion]
Indexing information
- F(ab')2 receptor [MeSH Supplementary Concept]
Manual BTNT mappings - CISMeF
- Immunoglobulin, F(ab')>2< fragment (substance) [SNOMED CT concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- immunoglobulin fab fragments [MeSH concept]
Related MeSH Supplementary Concept(s)
- (111)In-Fab-DTPA antimyosine [MeSH Supplementary Concept]
- 1E8-4b fab [MeSH Supplementary Concept]
- 64Cu-NOTA-ALT-836-Fab [MeSH Supplementary Concept]
- 99mTc-anti-carcinoembryonic antigen antibody [MeSH Supplementary Concept]
- AZD9773 [MeSH Supplementary Concept]
- COU-1 antibody [MeSH Supplementary Concept]
- CytoFab [MeSH Supplementary Concept]
- GL-7 fab fragment [MeSH Supplementary Concept]
- KB001 antibody [MeSH Supplementary Concept]
- RM4-TNF protein, recombinant [MeSH Supplementary Concept]
- T101 FAB fragment-ricin A-chain immunotoxin [MeSH Supplementary Concept]
- Viperfav [MeSH Supplementary Concept]
- antibody aldolase [MeSH Supplementary Concept]
- crotalidae polyvalent immune fab [MeSH Supplementary Concept]
- dapirolizumab pegol [MeSH Supplementary Concept]
- digoxin antibodies Fab fragments [MeSH Supplementary Concept]
- fab F11.2.32 [MeSH Supplementary Concept]
- fab MOR03268 [MeSH Supplementary Concept]
- immunoglobulin facb fragment [MeSH Supplementary Concept]
- lampalizumab [MeSH Supplementary Concept]
- protein kau, fab fragment [MeSH Supplementary Concept]
- technetium tc 99m-Fab'-RP-1 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Fab Fragment [NCIt concept]
- Immunoglobulin, F(ab) fragment (substance) [SNOMED CT concept]
- immunoglobulin, f(ab) fragment [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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