Preferred Label : digoxin;

MeSH definition : A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666);

CISMeF synonym : lilly brand of digoxin; bertek brand of digoxin; UDL brand of digoxin; R.A.N. brand of digoxin; glaxo wellcome brand of digoxin; GlaxoSmithKline brand 1 of digoxin; virco brand of digoxin; proctor & gamble brand of digoxin; AWD.pharma brand of digoxin; kern brand of digoxin; teofarma brand of digoxin; GlaxoSmithKline brand 2 of digoxin; novartis brand of digoxin; roche brand of digoxin;

MeSH hyponym : digoregen; dilanacin; lanoxicaps; mapluxin; lanoxin; digoxina boehringer; digacin; digitek; digoxine nativelle; lanicor; lanacordin; Boehringer, Digoxina; Nativelle, Digoxine; Hemigoxine Nativelle; Nativelle, Hemigoxine; Lanoxin-PG; Lanoxin PG; Lenoxin;

MeSH CAS label : Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-;

MeSH Related Number : 20830-75-5 (Digoxin);

Registry Number MeSH : 20830-75-5;

MeSH annotation : do not confuse with DIGITOXIN;

Wikipedia link : https://en.wikipedia.org/wiki/Digoxin;

Codes EINECS : 244-068-1;

Is substance : O;

UNII : 73K4184T59;

InChIKey : LTMHDMANZUZIPE-PUGKRICDSA-N;

Details


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A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

https://ansm.sante.fr/actualites/difficultes-dapprovisionnement-en-digoxine-nativelle-0-25-mg-hemigoxine-nativelle-0-125-mg-peut-etre-dispense-en-remplacement-a-condition-dadapter-la-posologie
2024
false
false
false
France
French
guidelines for drug use
digoxin
digoxin
drug substitution

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https://pharmactuel.com/index.php/pharmactuel/article/view/1311
2019
false
false
false
Canada
digoxin
atrial fibrillation
journal article
atrial fibrillation
digoxin
cause of death

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https://pharmactuel.com/index.php/pharmactuel/article/view/1273
2019
false
false
false
Canada
atrial fibrillation
anti-arrhythmia agents
cause of death
risk assessment
digoxin
anti-arrhythmia agents
critical appraisal or critical reading
digoxin
atrial fibrillation

---
https://pharmacomedicale.org/medicaments/par-specialites/item/digitaliques
2018
false
false
false
France
digoxin
cardiotonic agents
heart failure
anti-arrhythmia agents
arrhythmias, cardiac
digoxin
digoxin
continuity of patient care
drug information
digitalis glycosides

---
http://www.centreantipoisons.be/professionnels-de-la-sant/articles-pour-professionnels-de-la-sant/intoxications-aigu-s-et-antidote-8
false
true
false
Belgium
patient education handout
digoxin antibodies Fab fragments
digoxin
immunoglobulin fab fragments

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https://www.revmed.ch/RMS/2016/RMS-N-535/Utilisation-de-la-digoxine-dans-la-fibrillation-auriculaire
2016
false
false
false
Switzerland
French
journal article
atrial fibrillation
digoxin
atrial fibrillation
digoxin

---
https://minerva-ebp.be/FR/Analysis/430
2015
false
true
false
Belgium
French
scientific and technical information
french abstract
digoxin
treatment outcome
heart failure
digoxin
atrial fibrillation

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https://www.jle.com/fr/revues/medecine/gpn/e-docs/00/04/7F/5C/resume.phtml
2012
France
French
journal article
digitalis glycosides
anti-arrhythmia agents
cardiotonic agents
Drug-Related side effects and adverse reactions
aged
Drug-Related side effects and adverse reactions
digoxin

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http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61917063
2012
France
summary of product characteristics
package leaflet
digoxin
gout
ophthalmic solutions

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65458013
2012
France
summary of product characteristics
package leaflet
adulthood
injections
adult
digoxin

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http://www.has-sante.fr/portail/jcms/c_1036266/digoxine-hemigoxine
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-03/digoxine_hemidigoxine_-_ct-_9549.pdf
2011
France
French
digoxin
administration, oral
injections
digoxin
insurance, health, reimbursement
anti-arrhythmia agents
cardiotonic agents
treatment outcome
evaluation of the transparency committee

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http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67681303
http://agence-prd.ansm.sante.fr/php/ecodex/frames.php?specid=67681303&typedoc=R&ref=R0169345.htm
http://agence-prd.ansm.sante.fr/php/ecodex/frames.php?specid=67681303&typedoc=N&ref=N0169345.htm
2010
France
French
tablets
digoxin
digoxin
administration, oral
cardiotonic agents
cardiotonic agents
anti-arrhythmia agents
anti-arrhythmia agents
heart failure
arrhythmias, cardiac
supraventricular arrhythmia, nos
adult
aged
drug interactions
pregnancy
digoxin
summary of product characteristics
package leaflet

---
http://www.aboutkidshealth.ca/en/healthaz/drugs/pages/digoxin.aspx?k=digoxine
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Digoxin.aspx
2010
Canada
English
French
anti-arrhythmia agents
child
digoxin
digoxin
anti-arrhythmia agents
cardiotonic agents
cardiotonic agents
digoxin
administration, oral
injections
patient education handout
drug information

---
https://www.hug.ch/sites/interhug/files/structures/pharmacologie_et_toxicologie_cliniques/documents/cappinfo43.pdf
2007
Switzerland
journal article
Poisoning
poisoning
poisoning by digoxin
digoxin

---
http://www.has-sante.fr/portail/display.jsp?id=c_400715
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct032292.pdf
2005
France
French
tablets
digoxin
administration, oral
anti-arrhythmia agents
cardiotonic agents
insurance, health, reimbursement
digoxin
supraventricular arrhythmia, nos
arrhythmias, cardiac
heart failure
evaluation of the transparency committee

---
http://www.toxi.ch/upload/pdf/08_Digoxine.pdf
2003
Switzerland
French
digoxin
poisoning
emergency treatment
digitalis glycosides
scientific and technical information

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24/05/2025


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