Preferred Label : Alemtuzumab;
MeSH definition : An anti-CD52 ANTIGEN monoclonal antibody used for the treatment of certain types of
CD52-positive lymphomas (e.g., CHRONIC LYMPHOCYTIC LEUKEMIA; CUTANEOUS T-CELL LYMPHOMA;
and T-CELL LYMPHOMA). Its mode of actions include ANTIBODY-DEPENDENT CELL CYTOTOXICITY.;
DeCS synonym : MabCambath; Lemtrada; Campath 1M; Campath 1G; Campath 1H; Campath;
MeSH hyponym : Monoclonal Antibody Campath-1H; Antibody Campath-1H, Monoclonal; Campath-1H, Monoclonal Antibody; Monoclonal Antibody Campath 1H; Campath-1H; Campath1H; Campath-1M; Campath-1-G; Campath 1 G; Campath1G; Campath-1G;
UNII : 3A189DH42V;
Origin ID : D000074323;
UMLS CUI : C0383429;
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
Record concept(s)
See also
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
Validated automatic mappings to NTBT
An anti-CD52 ANTIGEN monoclonal antibody used for the treatment of certain types of
CD52-positive lymphomas (e.g., CHRONIC LYMPHOCYTIC LEUKEMIA; CUTANEOUS T-CELL LYMPHOMA;
and T-CELL LYMPHOMA). Its mode of actions include ANTIBODY-DEPENDENT CELL CYTOTOXICITY.
https://www.cochrane.org/fr/CD011203/MS_lalemtuzumab-dans-la-sclerose-en-plaques
2023
false
true
false
false
France
United Kingdom
Alemtuzumab
multiple sclerosis
Interferon beta-1a
multiple sclerosis, relapsing-remitting
Glatiramer Acetate
At increased risk for relapse (finding)
review of literature
french abstract
---
https://ansm.sante.fr/tableau-marr/alemtuzumab
2023
false
false
false
France
French
risk management
Alemtuzumab
Alemtuzumab
alemtuzumab
infusions, intravenous
continuity of patient care
multiple sclerosis, relapsing-remitting
guidelines for drug use
patients guideline
patient education as topic
Drug-Related side effects and adverse reactions
drug monitoring
clinical chemistry tests
thyroid diseases
purpura, thrombocytopenic, idiopathic
kidney diseases
anti-glomerular basement membrane disease
Infections
pregnancy
mass screening
Contraindications, Drug
premedication
---
MabCampath (alemtuzumab) - Risk of Haemophagocytic Lymphohistiocytosis, Stroke (including
ischaemic and haemorrhagic stroke), and Glomerulonephritis
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2020/73387a-fra.php
2020
false
false
false
Canada
French
English
pharmacovigilance note
Alemtuzumab
infusions, intravenous
alemtuzumab
risk
stroke
lymphohistiocytosis, hemophagocytic
glomerulonephritis
canada
leukemia, lymphocytic, chronic, B-Cell
Antineoplastic Agents, Immunological
---
https://ansm.sante.fr/informations-de-securite/lemtrada-alemtuzumab-restrictions-dindication-contre-indications-supplementaires-et-mesures-de-reduction-du-risque
2020
false
false
false
France
French
Alemtuzumab
Alemtuzumab
risk management
alemtuzumab
Alemtuzumab
pharmacovigilance note
guidelines for drug use
autoimmune diseases
heart diseases
multiple sclerosis, relapsing-remitting
adult
continuity of patient care
drug monitoring
infusions, intravenous
---
LEMTRADA (alemtuzumab) - Risk of Autoimmune Hepatitis, Haemophagocytic Lymphohistiocytosis,
and Associated Serious Cardiovascular Reactions
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2019/71299a-fra.php
2019
false
false
false
Canada
French
English
pharmacovigilance note
infusions, intravenous
Alemtuzumab
multiple sclerosis, relapsing-remitting
risk
hepatitis, autoimmune
lymphohistiocytosis, hemophagocytic
continuity of patient care
cardiovascular diseases
guidelines for drug use
alemtuzumab
---
https://ansm.sante.fr/informations-de-securite/alemtuzumab-lemtrada-restrictions-dutilisation-en-raison-deffets-indesirables-graves
2019
false
false
false
France
French
Alemtuzumab
Alemtuzumab
alemtuzumab
multiple sclerosis, relapsing-remitting
adult
continuity of patient care
pharmacovigilance note
guidelines for drug use
infusions, intravenous
Chemical and Drug Induced Liver Injury
hepatitis, autoimmune
cardiovascular diseases
lymphohistiocytosis, hemophagocytic
---
https://www.has-sante.fr/portail/jcms/c_2877320/fr/lemtrada
2018
false
false
false
France
Alemtuzumab
treatment outcome
alemtuzumab
multiple sclerosis, relapsing-remitting
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_2590010/fr/lemtrada
http://www.has-sante.fr/portail/jcms/c_2590010/fr/lemtrada-alemtuzumab-immunosuppresseur-selectif
https://www.has-sante.fr/portail/jcms/c_2590010/fr/lemtrada-alemtuzumab-immunosuppresseur-selectif
2016
false
false
false
false
France
French
evaluation of the transparency committee
alemtuzumab
infusions, intravenous
multiple sclerosis, relapsing-remitting
treatment outcome
insurance, health, reimbursement
guidelines for drug use
immunosuppressive agents
immunosuppressive agents
Alemtuzumab
Alemtuzumab
---
https://www.ema.europa.eu/medicines/human/EPAR/Lemtrada
2013
false
United Kingdom
French
English
Alemtuzumab
Alemtuzumab
alemtuzumab
drug approval
europe
treatment outcome
pharmacovigilance
infusions, intravenous
adult
multiple sclerosis, relapsing-remitting
contraception
pregnancy
breast feeding
fertility
drug evaluation, preclinical
summary of product characteristics
package leaflet
syndication feed
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
http://www.cochrane.org/fr/CD008078
2012
false
false
false
United Kingdom
France
antineoplastic agents
antibodies, monoclonal, humanized
treatment outcome
alemtuzumab
Alemtuzumab
meta-analysis
french abstract
leukemia, lymphocytic, chronic, B-Cell
---
https://www.ema.europa.eu/medicines/human/EPAR/MabCampath
2012
false
United Kingdom
English
French
alemtuzumab
syndication feed
Alemtuzumab
Alemtuzumab
antineoplastic agents
drug approval
treatment outcome
drug labeling
infusions, intravenous
adult
drug interactions
antineoplastic agents
breast feeding
pregnancy
drug screening assays, antitumor
drug storage
drug compounding
leukemia, lymphocytic, chronic, B-Cell
summary of product characteristics
package leaflet
drug evaluation
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized
---
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2008/14512a-fra.php
2008
false
Canada
French
alemtuzumab
Alemtuzumab
antineoplastic agents
Infections
leukemia, lymphocytic, chronic, B-Cell
consolidation chemotherapy
pharmacovigilance note
---
http://www.msss.gouv.qc.ca/sujets/organisation/lutte-contre-le-cancer/documents/guides-cepo-pdf/CEPO-Alemtuzumab_et_LLC_%C3%A0_lymphocytes_B_(2008-09).pdf
2008
false
false
Canada
French
alemtuzumab
antineoplastic agents
quebec
injections, intravenous
injections, subcutaneous
bibliography of medicine
Evidence-Based medicine
antineoplastic combined chemotherapy protocols
Alemtuzumab
leukemia, lymphocytic, chronic, B-Cell
leukemia, lymphocytic, chronic, B-Cell
guidelines for drug use
---
https://www.cadth.ca/sites/default/files/pdf/281_alemtuzumab_cetap_f.pdf
https://www.cadth.ca/sites/default/files/pdf/281_alemtuzumab_cetap_e.pdf
2005
false
Canada
English
French
alemtuzumab
CD52 Antigen
Alemtuzumab
Alemtuzumab
antineoplastic agents
antineoplastic agents
treatment outcome
canada
united states
randomized controlled trials as topic
antigens, neoplasm
glycoproteins
survival analysis
leukemia, lymphocytic, chronic, B-Cell
antigens, neoplasm
glycoproteins
drug evaluation
---
https://www.cadth.ca/sites/default/files/pdf/108_No56_alemtuzumab_edrug_f.pdf
2004
false
Canada
French
alemtuzumab
Alemtuzumab
clinical trials as topic
antineoplastic agents
leukemia, lymphocytic, chronic, B-Cell
drug evaluation
---
https://www.cadth.ca/sites/default/files/pdf/108_No16_alemtuzumab_edrug_e.pdf
https://www.cadth.ca/sites/default/files/pdf/108_No16_alemtuzumab_edrug_f.pdf
2001
false
Canada
French
English
alemtuzumab
Alemtuzumab
Alemtuzumab
leukemia, lymphocytic, chronic, B-Cell
antineoplastic agents
canada
treatment outcome
Evidence-Based medicine
united states
antineoplastic agents
CD52 Antigen
antigens, neoplasm
glycoproteins
antigens, neoplasm
glycoproteins
drug evaluation
---